User profiles for "author:Mathieu C Tamby"
Mathieu C. TambyResearcher, INSERM Verified email at inserm.fr Cited by 2345 |
New insights into the pathogenesis of systemic sclerosis
MC Tamby, Y Chanseaud, L Guillevin, L Mouthon - Autoimmunity reviews, 2003 - Elsevier
Systemic sclerosis (SSc) is a connective tissue disorder characterized by vascular
abnormalities and excessive collagen synthesis. Extracellular matrix overproduction by …
abnormalities and excessive collagen synthesis. Extracellular matrix overproduction by …
The role of inflammation and autoimmunity in the pathophysiology of pulmonary arterial hypertension
N Kherbeck, MC Tamby, G Bussone, H Dib… - Clinical reviews in …, 2013 - Springer
Pulmonary arterial hypertension is characterized by a remodeling of pulmonary arteries with
endothelial cell, fibroblast, and vascular smooth muscle cell activation and proliferation …
endothelial cell, fibroblast, and vascular smooth muscle cell activation and proliferation …
Pathogenesis of giant cell arteritis: More than just an inflammatory condition?
Giant cell arteritis (GCA) is characterized by intimal hyperplasia and luminal obstruction
leading to ischemic manifestations involving extra-cranial branches of carotid arteries and …
leading to ischemic manifestations involving extra-cranial branches of carotid arteries and …
Antibodies to fibroblasts in idiopathic and scleroderma-associated pulmonary hypertension
The aim of the present study was to investigate the presence of anti-fibroblast antibodies in
patients with idiopathic or scleroderma-associated pulmonary arterial hypertension (PAH) …
patients with idiopathic or scleroderma-associated pulmonary arterial hypertension (PAH) …
Identification of target antigens of antifibroblast antibodies in pulmonary arterial hypertension
Rationale: Pulmonary arterial hypertension (PAH) may be classified as idiopathic (IPAH) or
familial (FPAH) or associated with various conditions and exposures such as …
familial (FPAH) or associated with various conditions and exposures such as …
Targets of anti-endothelial cell antibodies in pulmonary hypertension and scleroderma
Anti-endothelial cell antibodies (AECAs) have been identified in patients with systemic
sclerosis (SSc) with and without pulmonary arterial hypertension (PAH) and in patients with …
sclerosis (SSc) with and without pulmonary arterial hypertension (PAH) and in patients with …
Microsomal Prostaglandin E2 Synthase-1 Modulates the Response to Vascular Injury
M Wang, K Ihida-Stansbury, D Kothapalli, MC Tamby… - Circulation, 2011 - Am Heart Assoc
Background—Microsomal (m) prostaglandin (PG) E2 synthase (S)-1 catalyzes the formation
of PGE2 from PGH2, a cyclooxygenase product that is derived from arachidonic acid …
of PGE2 from PGH2, a cyclooxygenase product that is derived from arachidonic acid …
Antifibroblast antibodies from systemic sclerosis patients bind to α-enolase and are associated with interstitial lung disease
Objective: To identify target antigens of antifibroblast antibodies (AFA) in systemic sclerosis
(SSc) patients. Patients and Methods: In the first part, sera from 24 SSc patients (12 with …
(SSc) patients. Patients and Methods: In the first part, sera from 24 SSc patients (12 with …
[HTML][HTML] Identification of target antigens of anti-endothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: a proteomic …
Introduction Immunological studies of giant cell arteritis (GCA) suggest that a triggering
antigen of unknown nature could generate a specific immune response. We thus decided to …
antigen of unknown nature could generate a specific immune response. We thus decided to …
IgG from patients with pulmonary arterial hypertension and/or systemic sclerosis binds to vascular smooth muscle cells and induces cell contraction
G Bussone, MC Tamby, C Calzas… - Annals of the …, 2012 - ard.bmj.com
Objectives Pulmonary arterial hypertension (PAH) is characterised by remodelling of
pulmonary arteries with enhanced vascular smooth muscle cell (VSMC) contraction …
pulmonary arteries with enhanced vascular smooth muscle cell (VSMC) contraction …