Proactive priming before the next pandemic could induce immune memory responses to
novel influenza antigens. In an open-label study, we analyzed B cell memory and antibody …

A comprehensive classification of metatarsalgia is proposed, including metatarsalgias
caused by systemic or extraregional disease, regional diseases and biomechanical …

Acute myeloid leukemia (AML) is a severe and often fatal systemic malignancy. Malignant
cells are capable of escaping host immune surveillance by inactivating cytotoxic lymphoid …

Immune responses to vaccination are tested in clinical trials. This process usually requires
years especially when immune memory and persistence are analyzed. Markers able to …

Human blood contains 2 populations of dendritic cells (DCs): plasmacytoid and myeloid
(mDC). mDCs are subdivided into 3 subsets using the surface markers CD16, CD1c, and …

Vasculitis are severe systemic autoimmune diseases which may involve different organs
and systems. Conversely, muscles do not represent an organ commonly involved by …

Vascular endothelial growth factor receptor-3 (VEGFR-3) plays a key role for the remodeling
of the primary capillary plexus in the embryo and contributes to angiogenesis and …

Chimeric antigen receptor (CAR)-redirected T lymphocytes are a promising
immunotherapeutic approach and object of pre-clinical evaluation for the treatment of acute …

Human cancer cells operate a variety of effective molecular and signaling mechanisms
which allow them to escape host immune surveillance and thus progress the disease. We …

Zika virus (ZIKV), a mosquito-borne flavivirus, causes devastating congenital birth defects.
We isolated a human monoclonal antibody (mAb), ZKA190, that potently cross-neutralizes …