User profiles for "author:M Hara"

Makoto R. Hara

Novartis
Verified email at novartis.com
Cited by 6007

[HTML][HTML] Cancer-associated fibroblasts: their characteristics and their roles in tumor growth

K Shiga, M Hara, T Nagasaki, T Sato, H Takahashi… - Cancers, 2015 - mdpi.com
Cancer tissues are composed of cancer cells and the surrounding stromal cells (eg,
fibroblasts, vascular endothelial cells, and immune cells), in addition to the extracellular …

Kabuki make‐up (Niikawa‐Kuroki) syndrome: A study of 62 patients

…, I Matsui, T Urakami, S Aritaki, M Hara… - American journal of …, 1988 - Wiley Online Library
These 62 patients with the Kabuki make‐up syndrome (KMS) were collected in a
collaborative study among 33 institutions and analyzed clinically, cytogenetically, and …

Pancreatic islet plasticity: interspecies comparison of islet architecture and composition

DJ Steiner, A Kim, K Miller, M Hara - Islets, 2010 - Taylor & Francis
The pancreatic islet displays diverse patterns of endocrine cell arrangement. The prototypic
islet, with insulin-secreting β-cells forming the core surrounded by other endocrine cells in …

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

…, N Oda, NJ Cox, X Li, M Orho-Melander, M Hara… - Nature …, 2000 - nature.com
Type 2 or non-insulin-dependent diabetes mellitus (NIDDM) is the most common form of
diabetes worldwide, affecting approximately 4% of the world's adult population. It is …

S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding

MR Hara, N Agrawal, SF Kim, MB Cascio… - Nature cell …, 2005 - nature.com
Abstract Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) influences cytotoxicity,
translocating to the nucleus during apoptosis. Here we report a signalling pathway in which …

[HTML][HTML] Biodiesel made with sugar catalyst

…, M Okamura, JN Kondo, S Hayashi, K Domen, M Hara - Nature, 2005 - nature.com
The production of diesel from vegetable oil calls for an efficient solid catalyst to make the
process fully ecologically friendly. Here we describe the preparation of such a catalyst from …

Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

H Nishimura, T Okazaki, Y Tanaka, K Nakatani, M Hara… - Science, 2001 - science.org
Dilated cardiomyopathy is a severe pathology of the heart with poorly understood etiology.
Disruption of the gene encoding the negative immunoregulatory receptor PD-1 in BALB/c …

Hydrolysis of Cellulose by Amorphous Carbon Bearing SO3H, COOH, and OH Groups

…, D Yamaguchi, H Kato, S Hayashi, M Hara - Journal of the …, 2008 - ACS Publications
The hydrolysis of cellulose into saccharides using a range of solid catalysts is investigated
for potential application in the environmentally benign saccharification of cellulose …

Ammonia synthesis using a stable electride as an electron donor and reversible hydrogen store

…, S Matsuishi, T Yokoyama, SW Kim, M Hara… - Nature …, 2012 - nature.com
Industrially, the artificial fixation of atmospheric nitrogen to ammonia is carried out using the
Haber–Bosch process, but this process requires high temperatures and pressures, and …

Identification of melatonin in plants and its effects on plasma melatonin levels and binding to melatonin receptors in vertebrates.

…, K Yamamoto, R Ohtani-Kaneko, M Hara… - Biochemistry and …, 1995 - europepmc.org
Twenty-four edible plants were investigated for the presence of melatonin, heretofore
considered to be a molecule found only in the animal kingdom. The amount of melatonin in …