[HTML][HTML] Association between bone mineral density and type 2 diabetes mellitus: a meta-analysis of observational studies

L Ma, L Oei, L Jiang, K Estrada, H Chen… - European journal of …, 2012 - Springer
Type 2 diabetes mellitus (T2DM) influences bone metabolism, but the relation of T2DM with
bone mineral density (BMD) remains inconsistent across studies. The objective of this study …

Deletion of BACH1 attenuates atherosclerosis by reducing endothelial inflammation

M Jia, Q Li, J Guo, W Shi, L Zhu, Y Huang, Y Li… - Circulation …, 2022 - Am Heart Assoc
Background: The transcription factor BACH1 (BTB and CNC homology 1) suppressed
endothelial cells (ECs) proliferation and migration and impaired angiogenesis in the …

[HTML][HTML] The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response

Q Wang, L Huang, Z Hong, Z Lv, Z Mao, Y Tang… - PLoS …, 2017 - journals.plos.org
The cyclic GMP-AMP synthase (cGAS), upon cytosolic DNA stimulation, catalyzes the
formation of the second messenger 2′ 3′-cGAMP, which then binds to stimulator of …

[PDF][PDF] The critical role of IL-6 in the pathogenesis of Takayasu arteritis

X Kong, Y Sun, L Ma, H Chen, L Wei, W Wu… - Clin Exp …, 2016 - clinexprheumatol.org
Objective. To investigate T cell subsets and immune cytokine profiles in untreated Takayasu
arteritis (TAK) patients and the underlying immunopathological mechanism. Methods. We …

Evaluation of Takayasu arteritis activity by delayed contrast-enhanced magnetic resonance imaging

L Jiang, D Li, F Yan, X Dai, Y Li, L Ma - International journal of cardiology, 2012 - Elsevier
BACKGROUND: To measure and assess the disease activity of Takayasu arteritis (TA)
quantitatively by magnetic resonance angiography (MRA). METHODS: Twenty-six Chinese …

An allopurinol‐controlled, multicenter, randomized, double‐blind, parallel between‐group, comparative study of febuxostat in C hinese patients with gout and …

X Huang, H Du, J Gu, D Zhao, L Jiang… - … journal of rheumatic …, 2014 - Wiley Online Library
Aim Febuxostat, a novel non‐purine selective inhibitor of xanthine oxidase, has been
identified as a potential alternative to allopurinol in patients with hyperuricemia. The purpose …

Treatment efficacy and safety of tofacitinib versus methotrexate in Takayasu arteritis: a prospective observational study

X Kong, Y Sun, X Dai, L Wang, Z Ji, H Chen… - Annals of the …, 2022 - ard.bmj.com
Objective To compare the treatment efficacy and safety of tofacitinib (TOF) versus
methotrexate (MTX) in Takayasu arteritis (TAK). Methods Fifty-three patients with active …

Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans

L Jiang, J Yin, L Ye, J Yang, G Hemani… - Arthritis & …, 2014 - Wiley Online Library
Objective To investigate differences in genetic risk factors for rheumatoid arthritis (RA) in
Han Chinese as compared with Europeans. Methods A genome‐wide association study was …

BACH1 deficiency prevents neointima formation and maintains the differentiated phenotype of vascular smooth muscle cells by regulating chromatin accessibility

J Guo, J Qiu, M Jia, Q Li, X Wei, L Li, Q Pan… - Nucleic Acids …, 2023 - academic.oup.com
The transcription factor BTB and CNC homology 1 (BACH1) has been linked to coronary
artery disease risk by human genome-wide association studies, but little is known about the …

[HTML][HTML] The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor γt (RORγt) in Th17 cells

L Han, J Yang, X Wang, Q Wu, S Yin, Z Li… - Journal of Biological …, 2014 - ASBMB
Stable retinoic acid-related orphan nuclear receptor γt (RORγt) expression is pivotal for the
development and function of Th17 cells. Here we demonstrate that expression of the …