[HTML][HTML] The maintenance of memory plasma cells
L Khodadadi, Q Cheng, A Radbruch… - Frontiers in …, 2019 - frontiersin.org
It is now well accepted that plasma cells can become long-lived (memory) plasma cells and
secrete antibodies for months, years or a lifetime. However, the mechanisms involved in this …
secrete antibodies for months, years or a lifetime. However, the mechanisms involved in this …
[HTML][HTML] Pathogenic memory plasma cells in autoimmunity
Pathogenic memory plasma cells in autoimmunity - PMC Back to Top Skip to main content NIH
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Integrative analysis reveals a molecular stratification of systemic autoimmune diseases
Objective Clinical heterogeneity, a hallmark of systemic autoimmune diseases, impedes
early diagnosis and effective treatment, issues that may be addressed if patients could be …
early diagnosis and effective treatment, issues that may be addressed if patients could be …
Proteasome inhibition with bortezomib induces a therapeutically relevant depletion of plasma cells in SLE but does not target their precursors
T Alexander, Q Cheng, J Klotsche… - European journal of …, 2018 - Wiley Online Library
Long‐lived plasma cells (PCs) not only provide protective humoral immunity, they are also
an essential component of the autoreactive immunologic memory that may drive chronic …
an essential component of the autoreactive immunologic memory that may drive chronic …
Autoantibodies from long-lived 'memory'plasma cells of NZB/W mice drive immune complex nephritis
Q Cheng, IM Mumtaz, L Khodadadi… - Annals of the …, 2013 - ard.bmj.com
Objectives We have previously shown that both short-and long-lived plasma cells (PCs)
significantly contribute to autoantibody production in NZB/W mice as a model of lupus …
significantly contribute to autoantibody production in NZB/W mice as a model of lupus …
[HTML][HTML] Bortezomib plus continuous B cell depletion results in sustained plasma cell depletion and amelioration of lupus nephritis in NZB/W F1 mice
L Khodadadi, Q Cheng, T Alexander, Ö Sercan-Alp… - PloS one, 2015 - journals.plos.org
Long-lived plasma cells (LLPCs) are an unmet therapeutic challenge, and developing
strategies for their targeting is an emerging goal of autoantibody-mediated diseases such as …
strategies for their targeting is an emerging goal of autoantibody-mediated diseases such as …
[HTML][HTML] Long-lived plasma cells are early and constantly generated in New Zealand Black/New Zealand White F1 mice and their therapeutic depletion requires a …
A Taddeo, L Khodadadi, C Voigt, IM Mumtaz… - Arthritis research & …, 2015 - Springer
Introduction Autoantibodies contribute significantly to the pathogenesis of systemic lupus
erythematosus (SLE). Unfortunately, the long-lived plasma cells (LLPCs) secreting such …
erythematosus (SLE). Unfortunately, the long-lived plasma cells (LLPCs) secreting such …
CXCR4–CXCL12 interaction is important for plasma cell homing and survival in NZB/W mice
Q Cheng, L Khodadadi, A Taddeo… - European Journal of …, 2018 - Wiley Online Library
Abstract Antibody‐secreting cells (ASCs), including short‐lived plasmablasts and long‐lived
memory plasma cells (LLPCs), contribute to autoimmune pathology. ASCs, particularly …
memory plasma cells (LLPCs), contribute to autoimmune pathology. ASCs, particularly …
Selective depletion of plasma cells in vivo based on the specificity of their secreted antibodies
Q Cheng, A Pelz, A Taddeo… - European journal of …, 2020 - Wiley Online Library
Antibody‐mediated diseases affect more than 10% of the human population. For most, no
cure is available, particularly when the pathogenic antibodies are secreted by long‐lived …
cure is available, particularly when the pathogenic antibodies are secreted by long‐lived …
Intraepidermal injection of dissociated epidermal cell suspension improves vitiligo
L Khodadadi, S Shafieyan, M Sotoudeh… - Archives of …, 2010 - Springer
This study was initiated to evaluate the safety and effectiveness of intraepidermal injection of
dissociated epidermal cells into the lesions of stable vitiligo patients. Autologous dissociated …
dissociated epidermal cells into the lesions of stable vitiligo patients. Autologous dissociated …