Psoriasis is associated with several comorbidities ranging from cardiovascular comorbidity
and mental disorders to other immune mediated inflammatory diseases. However, most of …

Axial spondyloarthritis (axSpA), psoriatic arthritis (PsA), psoriasis, inflammatory bowel
disease (IBD), and noninfectious uveitis form a distinct group among the immune mediated …

Objective To compare the efficacy and safety of brodalumab, an interleukin-17 receptor
subunit A inhibitor, with placebo, in patients with psoriatic arthritis (PsA). Methods Adult …

Background Psoriasis and atopic dermatitis (AD) are immuno-inflammatory diseases that
can result in lifelong systemic inflammation. Unlike AD, psoriasis has been associated with …

Importance Inflammatory pathways of psoriasis share similarities with the mechanisms
identified in atherosclerosis, and the association between psoriasis and cardiovascular …

Objectives (i) To estimate the prevalence and severity of coronary artery disease and (ii) to
assess the risk of cardiovascular events and mortality, in patients with psoriasis and psoriatic …

Background Clinical trials have shown promising results for interleukin-23 inhibitors in the
treatment of psoriasis. The drugs have been used in clinical practice since 2017. Objective …

Objective Atopic dermatitis (AD) is an inflammatory skin disorder with a childhood
prevalence reaching 20%. An estimated 50% of patients have a life-long chronic course …

Background Clinical trials have established the efficacy of brodalumab in treatment of
psoriasis and psoriatic arthritis. Real-world evidence is needed to fully evaluate the drug …

Background: Unlicensed use of melanotan-II (MT-II) to promote skin pigmentation has
become prevalent amongst young people attending fitness centres. We present a case …