User profiles for "author:Kaspar Rufibach"

Kaspar Rufibach

F. Hoffmann-La Roche
Verified email at roche.com
Cited by 7090

[HTML][HTML] Obinutuzumab for the first-line treatment of follicular lymphoma

R Marcus, A Davies, K Ando, W Klapper… - … England Journal of …, 2017 - Mass Medical Soc
Background Rituximab-based immunochemotherapy has improved outcomes in patients
with follicular lymphoma. Obinutuzumab is a glycoengineered type II anti-CD20 monoclonal …

[PDF][PDF] Docetaxel, cisplatin, and fluorouracil; docetaxel and cisplatin; and epirubicin, cisplatin, and fluorouracil as systemic treatment for advanced gastric carcinoma: a …

AD Roth, N Fazio, R Stupp, S Falk… - Journal of Clinical …, 2007 - academia.edu
Purpose This randomized phase II trial evaluated two docetaxel-based regimens to see
which would be most promising according to overall response rate (ORR) for comparison in …

[PDF][PDF] Concomitant cisplatin significantly improves locoregional control in advanced head and neck cancers treated with hyperfractionated radiotherapy

P Huguenin, KT Beer, A Allal, K Rufibach… - Journal of clinical …, 2004 - researchgate.net
Purpose To determine whether the application of two courses of cisplatin simultaneously
with hyperfractionated radiotherapy improves the outcome in locally advanced and/or …

Use of Brier score to assess binary predictions

K Rufibach - Journal of clinical epidemiology, 2010 - jclinepi.com
The use of the Brier score [1] in medical research to assess and compare the accuracy of
binary predictions or prediction models is increasingly popular; see, for example Refs.[2e5] …

A review of Bayesian perspectives on sample size derivation for confirmatory trials

K Kunzmann, MJ Grayling, KM Lee… - The American …, 2021 - Taylor & Francis
Sample size derivation is a crucial element of planning any confirmatory trial. The required
sample size is typically derived based on constraints on the maximal acceptable Type I error …

Intracoronary injection of bone marrow–derived mononuclear cells early or late after acute myocardial infarction: effects on global left ventricular function

D Sürder, R Manka, V Lo Cicero, T Moccetti… - Circulation, 2013 - Am Heart Assoc
Background—Intracoronary administration of autologous bone marrow–derived
mononuclear cells (BM-MNC) may improve remodeling of the left ventricle (LV) after acute …

Maximum likelihood estimation of a log-concave density and its distribution function: Basic properties and uniform consistency

L Dümbgen, K Rufibach - 2009 - projecteuclid.org
We study nonparametric maximum likelihood estimation of a log-concave probability density
and its distribution and hazard function. Some general properties of these estimators are …

Tumor necrosis factor α inhibition in radiographic and nonradiographic axial spondyloarthritis: results from a large observational cohort

A Ciurea, A Scherer, P Exer, J Bernhard… - Arthritis & …, 2013 - Wiley Online Library
Objective To evaluate the baseline characteristics of patients with radiographic axial
spondyloarthritis (SpA; ankylosing spondylitis [AS]) and patients with nonradiographic axial …

Frequency and anatomic distribution of magnetic resonance imaging features in the sacroiliac joints of young athletes: exploring “background noise” toward a data …

U Weber, AG Jurik, A Zejden, E Larsen… - Arthritis & …, 2018 - Wiley Online Library
Objective Low‐grade bone marrow edema (BME) has been reported in the sacroiliac (SI)
joints of 25% of healthy individuals and patients with nonspecific mechanical back pain, thus …

Predictors for efficacy of percutaneous mitral valve repair using the MitraClip system: the results of the MitraSwiss registry

D Sürder, G Pedrazzini, O Gaemperli, P Biaggi, C Felix… - Heart, 2013 - heart.bmj.com
Background Percutaneous mitral valve repair (MVR) using the MitraClip system has become
a valid alternative for patients with severe mitral regurgitation (MR) and high operative risk …