The gut microbiota and host health: a new clinical frontier
JR Marchesi, DH Adams, F Fava, GDA Hermes… - Gut, 2016 - gut.bmj.com
Over the last 10–15 years, our understanding of the composition and functions of the human
gut microbiota has increased exponentially. To a large extent, this has been due to new …
gut microbiota has increased exponentially. To a large extent, this has been due to new …
A bacterial driver–passenger model for colorectal cancer: beyond the usual suspects
H Tjalsma, A Boleij, JR Marchesi… - Nature Reviews …, 2012 - nature.com
Cancer has long been considered a genetic disease. However, accumulating evidence
supports the involvement of infectious agents in the development of cancer, especially in …
supports the involvement of infectious agents in the development of cancer, especially in …
Gut microbiota modulation of chemotherapy efficacy and toxicity
Evidence is growing that the gut microbiota modulates the host response to
chemotherapeutic drugs, with three main clinical outcomes: facilitation of drug efficacy; …
chemotherapeutic drugs, with three main clinical outcomes: facilitation of drug efficacy; …
Gut microbiota composition correlates with diet and health in the elderly
MJ Claesson, IB Jeffery, S Conde, SE Power… - Nature, 2012 - nature.com
Alterations in intestinal microbiota composition are associated with several chronic
conditions, including obesity and inflammatory diseases. The microbiota of older people …
conditions, including obesity and inflammatory diseases. The microbiota of older people …
Composition, variability, and temporal stability of the intestinal microbiota of the elderly
Alterations in the human intestinal microbiota are linked to conditions including inflammatory
bowel disease, irritable bowel syndrome, and obesity. The microbiota also undergoes …
bowel disease, irritable bowel syndrome, and obesity. The microbiota also undergoes …
The composition of the gut microbiota throughout life, with an emphasis on early life
JM Rodríguez, K Murphy, C Stanton… - Microbial ecology in …, 2015 - Taylor & Francis
The intestinal microbiota has become a relevant aspect of human health. Microbial
colonization runs in parallel with immune system maturation and plays a role in intestinal …
colonization runs in parallel with immune system maturation and plays a role in intestinal …
Design and evaluation of useful bacterium-specific PCR primers that amplify genes coding for bacterial 16S rRNA
JR Marchesi, T Sato, AJ Weightman… - Applied and …, 1998 - Am Soc Microbiol
We report the design and evaluation of PCR primers 63f and 1387r for amplification of 16S
rRNA genes from bacteria. Their specificity and efficacy were tested systematically with a …
rRNA genes from bacteria. Their specificity and efficacy were tested systematically with a …
[HTML][HTML] Comparative analysis of pyrosequencing and a phylogenetic microarray for exploring microbial community structures in the human distal intestine
Background Variations in the composition of the human intestinal microbiota are linked to
diverse health conditions. High-throughput molecular technologies have recently elucidated …
diverse health conditions. High-throughput molecular technologies have recently elucidated …
Early life stress alters behavior, immunity, and microbiota in rats: implications for irritable bowel syndrome and psychiatric illnesses
SM O'Mahony, JR Marchesi, P Scully, C Codling… - Biological …, 2009 - Elsevier
BACKGROUND: Adverse early life events are associated with a maladaptive stress
response system and might increase the vulnerability to disease in later life. Several …
response system and might increase the vulnerability to disease in later life. Several …
[HTML][HTML] The vocabulary of microbiome research: a proposal
JR Marchesi, J Ravel - Microbiome, 2015 - Springer
The advancement of DNA/RNA, proteins, and metabolite analytical platforms, combined with
increased computing technologies, has transformed the field of microbial community …
increased computing technologies, has transformed the field of microbial community …