Efficacy and safety of golimumab in patients with ankylosing spondylitis: results of a randomized, double‐blind, placebo‐controlled, phase III trial

RD Inman, JC Davis Jr, DVD Heijde… - … : Official Journal of …, 2008 - Wiley Online Library
Objective To evaluate the efficacy and safety of golimumab in patients with ankylosing
spondylitis (AS) in the GO‐RAISE study. Methods Patients with active AS, a Bath AS Disease …

Risk factors for drug dependence among out‐patients on opioid therapy in a large US health‐care system

JA Boscarino, M Rukstalis, SN Hoffman, JJ Han… - …, 2010 - Wiley Online Library
Aims Our study sought to assess the prevalence of and risk factors for opioid drug
dependence among out‐patients on long‐term opioid therapy in a large health‐care system …

Predictors of joint damage in patients with early rheumatoid arthritis treated with high‐dose methotrexate with or without concomitant infliximab: results from the …

JS Smolen, DMFM Van Der Heijde… - Arthritis & …, 2006 - Wiley Online Library
Objective. To identify disease characteristics lead-ing to progression of joint damage in
patients with early rheumatoid arthritis (RA) treated with methotrexate (MTX) versus those …

Golimumab in patients with active rheumatoid arthritis despite treatment with methotrexate: a randomized, double‐blind, placebo‐controlled, dose‐ranging study

J Kay, EL Matteson, B Dasgupta, P Nash… - Arthritis & …, 2008 - Wiley Online Library
Objective To assess the efficacy, safety, and pharmacology of subcutaneous administration
of golimumab in patients with active rheumatoid arthritis (RA) despite treatment with …

The safety of infliximab, combined with background treatments, among patients with rheumatoid arthritis and various comorbidities: a large, randomized, placebo …

R Westhovens, D Yocum, J Han, A Berman… - Arthritis & …, 2006 - Wiley Online Library
Objective To assess the risk of serious infections following 22 weeks of infliximab therapy,
and to further characterize the safety profile of infliximab in combination with background …

Radiographic changes in rheumatoid arthritis patients attaining different disease activity states with methotrexate monotherapy and infliximab plus methotrexate: the …

JS Smolen, C Han, DMFM van der Heijde… - Annals of the …, 2009 - ard.bmj.com
Objective: To examine the association of radiographic progression and disease activity
states in patients with rheumatoid arthritis (RA) treated with methotrexate with or without …

Treatment with infliximab plus methotrexate improves anemia in patients with rheumatoid arthritis independent of improvement in other clinical outcome measures—a …

MK Doyle, MU Rahman, C Han, J Han, J Giles… - Seminars in arthritis and …, 2009 - Elsevier
OBJECTIVE: To evaluate the effect of antitumor necrosis factor-alpha monoclonal antibody
infliximab treatment on anemia in patients with rheumatoid arthritis (RA). METHODS: Data …

Major reduction in spinal inflammation in patients with ankylosing spondylitis after treatment with infliximab: results of a multicenter, randomized, double‐blind …

J Braun, R Landewé, KGA Hermann… - … : Official Journal of …, 2006 - Wiley Online Library
Objective To determine whether the effects of anti–tumor necrosis factor α (TNFα) in
reducing the signs and symptoms of ankylosing spondylitis (AS) coincide with a reduction in …

Prevalence of prescription opioid-use disorder among chronic pain patients: comparison of the DSM-5 vs. DSM-4 diagnostic criteria

JA Boscarino, MR Rukstalis, SN Hoffman… - Journal of addictive …, 2011 - Taylor & Francis
The authors estimated the prevalence of lifetime prescription opioid-use disorder among
outpatients on opioid therapy using criteria from both versions 4 and 5 of the Diagnostic and …

Effects of infliximab on markers of inflammation and bone turnover and associations with bone mineral density in patients with ankylosing spondylitis

S Visvanathan, D van der Heijde, A Deodhar… - Annals of the …, 2009 - ard.bmj.com
Objectives: To evaluate the relationship between bone mineral density (BMD) and
biomarkers of bone turnover and inflammation in patients with ankylosing spondylitis (AS) …