User profiles for "author:Jeremy Sokolove"
jeremy sokoloveStanford University Verified email at stanford.edu Cited by 10225 |
Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis
Osteoarthritis (OA) has long been viewed as a degenerative disease of cartilage, but
accumulating evidence indicates that inflammation has a critical role in its pathogenesis …
accumulating evidence indicates that inflammation has a critical role in its pathogenesis …
Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations
J Sokolove, CM Lepus - Therapeutic advances in …, 2013 - journals.sagepub.com
Osteoarthritis (OA) has traditionally been classified as a noninflammatory arthritis; however,
the dichotomy between inflammatory and degenerative arthritis is becoming less clear with …
the dichotomy between inflammatory and degenerative arthritis is becoming less clear with …
Mechanistic biomarkers for clinical decision making in rheumatic diseases
WH Robinson, TM Lindstrom, RK Cheung… - Nature Reviews …, 2013 - nature.com
The use of biomarkers is becoming increasingly intrinsic to the practice of medicine and
holds great promise for transforming the practice of rheumatology. Biomarkers have the …
holds great promise for transforming the practice of rheumatology. Biomarkers have the …
[HTML][HTML] Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis
Rheumatoid arthritis (RA) is a prototypical autoimmune arthritis affecting nearly 1% of the
world population and is a significant cause of worldwide disability. Though prior studies …
world population and is a significant cause of worldwide disability. Though prior studies …
Aggregatibacter actinomycetemcomitans–induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis
MF Konig, L Abusleme, J Reinholdt… - Science translational …, 2016 - science.org
A bacterial etiology of rheumatoid arthritis (RA) has been suspected since the beginnings of
modern germ theory. Recent studies implicate mucosal surfaces as sites of disease …
modern germ theory. Recent studies implicate mucosal surfaces as sites of disease …
[PDF][PDF] Periodontitis and Porphyromonas gingivalis in Patients With Rheumatoid Arthritis
Objective To examine the degree to which shared risk factors explain the relationship of
periodontitis (PD) to rheumatoid arthritis (RA) and to determine the associations of PD and …
periodontitis (PD) to rheumatoid arthritis (RA) and to determine the associations of PD and …
Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll‐like receptor 4 and Fcγ receptor
J Sokolove, X Zhao, PE Chandra… - Arthritis & …, 2011 - Wiley Online Library
Objective Rheumatoid arthritis (RA) is associated with the presence of anti–citrullinated
protein antibodies (ACPAs). Nearly two‐thirds of patients with ACPA‐positive RA have …
protein antibodies (ACPAs). Nearly two‐thirds of patients with ACPA‐positive RA have …
[HTML][HTML] Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4
DH Sohn, J Sokolove, O Sharpe, JC Erhart… - Arthritis research & …, 2012 - Springer
Introduction Osteoarthritis (OA) is a degenerative disease characterized by cartilage
breakdown in the synovial joints. The presence of low-grade inflammation in OA joints is …
breakdown in the synovial joints. The presence of low-grade inflammation in OA joints is …
CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis
Objectives While various monocyte chemokine systems are increased in expression in
osteoarthritis (OA), the hierarchy of chemokines and chemokine receptors in mediating …
osteoarthritis (OA), the hierarchy of chemokines and chemokine receptors in mediating …
Rheumatoid factor as a potentiator of anti–citrullinated protein antibody–mediated inflammation in rheumatoid arthritis
J Sokolove, DS Johnson, LJ Lahey… - Arthritis & …, 2014 - Wiley Online Library
Objective The co‐occurrence of rheumatoid factor (RF) and anti–citrullinated protein
antibody (ACPA) positivity in rheumatoid arthritis (RA) is well described. However, the …
antibody (ACPA) positivity in rheumatoid arthritis (RA) is well described. However, the …