An international registry on autoinflammatory diseases: the Eurofever experience
Objective To report on the demographic data from the first 18 months of enrollment to an
international registry on autoinflammatory diseases in the context of the Eurofever project …
international registry on autoinflammatory diseases in the context of the Eurofever project …
Tumor necrosis factor-alpha blocker in treatment of juvenile idiopathic arthritis-associated uveitis refractory to second-line agents: results of a multinational survey.
I Foeldvari, S Nielsen, J Kümmerle-Deschner… - The Journal of …, 2007 - jrheum.org
OBJECTIVE: Uveitis occurs in 10%-15% of patients with juvenile idiopathic arthritis (JIA). If
topical treatment fails, second-line agents are used to control the disease. However, some …
topical treatment fails, second-line agents are used to control the disease. However, some …
[HTML][HTML] Localization and functionality of the inflammasome in neutrophils
M Bakele, M Joos, S Burdi, N Allgaier, S Pöschel… - Journal of Biological …, 2014 - ASBMB
Neutrophils represent the major fraction of circulating immune cells and are rapidly recruited
to sites of infection and inflammation. The inflammasome is a multiprotein complex that …
to sites of infection and inflammation. The inflammasome is a multiprotein complex that …
Human NACHT, LRR, and PYD domain–containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase
X Liu, T Pichulik, OO Wolz, TM Dang, A Stutz… - Journal of Allergy and …, 2017 - Elsevier
Background The Nod-like receptor NACHT, LRR, and PYD domain–containing protein 3
(NLRP3) and Bruton tyrosine kinase (BTK) are protagonists in innate and adaptive immunity …
(NLRP3) and Bruton tyrosine kinase (BTK) are protagonists in innate and adaptive immunity …
MRI findings in psoriatic arthritis of the hands
D Spira, I Kötter, J Henes… - American Journal of …, 2010 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this essay is to provide a practical review of the spectrum of
morphologic and functional MRI findings in psoriatic arthritis of the hand joints …
morphologic and functional MRI findings in psoriatic arthritis of the hand joints …
Baricitinib in juvenile idiopathic arthritis: an international, phase 3, randomised, double-blind, placebo-controlled, withdrawal, efficacy, and safety trial
AV Ramanan, P Quartier, N Okamoto, I Foeldvari… - The Lancet, 2023 - thelancet.com
Background Juvenile idiopathic arthritis can be refractory to some or all treatment regimens,
therefore new medications are needed to treat this population. This trial assessed the …
therefore new medications are needed to treat this population. This trial assessed the …
Localized scleroderma: MR findings and clinical features
S Schanz, G Fierlbeck, A Ulmer, M Schmalzing… - Radiology, 2011 - pubs.rsna.org
Purpose To describe musculoskeletal manifestations seen at magnetic resonance (MR)
imaging in patients with localized scleroderma (LS) and to examine the relationship of MR …
imaging in patients with localized scleroderma (LS) and to examine the relationship of MR …
Efficacy and safety of etanercept in patients with the enthesitis‐related arthritis category of juvenile idiopathic arthritis: results from a phase III randomized, double …
G Horneff, I Foeldvari, K Minden… - Arthritis & …, 2015 - Wiley Online Library
Objective To evaluate the efficacy and safety of etanercept in patients with enthesitis‐related
arthritis (ERA) in juvenile idiopathic arthritis (JIA). Methods This was a 2‐phase study in JIA …
arthritis (ERA) in juvenile idiopathic arthritis (JIA). Methods This was a 2‐phase study in JIA …
BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity
ZA Bittner, X Liu, M Mateo Tortola… - Journal of Experimental …, 2021 - rupress.org
Activity of the NLRP3 inflammasome, a critical mediator of inflammation, is controlled by
accessory proteins, posttranslational modifications, cellular localization, and …
accessory proteins, posttranslational modifications, cellular localization, and …
Risk factors for severe Muckle‐Wells syndrome
JB Kümmerle‐Deschner, PN Tyrrell… - Arthritis & …, 2010 - Wiley Online Library
Abstract Objective Muckle‐Wells syndrome (MWS) is an inherited autoinflammatory disease
resulting in excessive interleukin‐1 release. It is unknown whether demographic, clinical, or …
resulting in excessive interleukin‐1 release. It is unknown whether demographic, clinical, or …