Objective: To determine whether the human herpes viruses, cytomegalovirus (CMV), Epstein-
Barr virus (EBV), and human herpesvirus 6 (HHV-6), are detectable in serum and peripheral …

Objective: To evaluate the role of parvovirus B19 (B19), varicella zoster virus (VZV), and
human herpes virus 6 (HHV-6) in the aetiopathology of giant cell arteritis (GCA). Methods …

Objectives. The presence of anti-citrullinated peptide antibodies is the most specific
serological marker known of rheumatoid arthritis (RA). The PADI4 gene, encoding a …

Background Human endogenous retroviruses (HERVs) are genomic sequences that
resulted from ancestral germ-line infections by exogenous retroviruses and therefore are …

Objective: Genome-wide studies have identified the chromosomal region 16p13 in the
susceptibility to type 1 diabetes (T1D) and multiple sclerosis (MS). This region includes the …

Background The aim of this study was to evaluate, the existence of a signature of
differentially expressed microRNAs (miRNAs) during osteogenic differentiation of bone …

Objectives To elucidate disease-specific molecular changes occurring in osteoarthritis (OA)
by analysing the differential gene expression profiles of bone marrow mesenchymal stem …

Objective Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) share some
genetic factors such as HLA, PTPN22, STAT4, and 6q23. The aim of this study was to …

Objectives: To assess and compare the long-term drug survival (time to drug
discontinuation) of biological agents (BA) in patients with rheumatoid arthritis (RA) in clinical …

Introduction Osteoarthritis (OA) is characterized by altered homeostasis of joint cartilage and
bone, whose functional properties rely on chondrocytes and osteoblasts, belonging to …