Inflammatory mediators in the cervix, placenta and fetal membranes play a crucial role in
human parturition. The aim of this study was to determine whether the upper and lower …

The aim of this study was to investigate the presence of nitric oxide synthase (NOS) in
human uterus. Tissues were obtained at operation from 10 women undergoing hysterectomy …

Immunocytochemistry was used to localize endothelial (eNOS) and inducible (iNOS) nitric
oxide synthase in human uterine tissues collected at various stages of the menstrual cycle …

Animal studies have suggested that nitric oxide, a smooth muscle relaxant, is a fundamental
mediator in the initiation of parturition. The purpose of this study was to test the hypothesis …

The purpose of this study was to localize intercellular adhesion molecule (ICAM)-1 and
ICAM-2 in human endometrium and myometrium throughout the menstrual cycle, and to …

Background: It has been hypothesized that iron is stored in the synovium of patients with
rheumatoid arthritis which perpetuates inflammation by aiding the production of oxygen free …

Activation of class Ia PI3K (phosphoinositide 3-kinase) produces PtdIns P 3, a vital
intracellular mediator whose degradation generates additional lipid signals. In the present …

CRH and POMC-derived peptides are produced at a number of intrauterine sites in both the
nonpregnant and pregnant states. It is hypothesized that CRH and POMC-derived peptides …

Superoxide, an agent which attenuates the half-life of nitric oxide, is metabolized and
synthesized by superoxide dismutase (SOD) and xanthine oxidase, respectively. Over the …

Nitric oxide (NO), derived from L-arginine by the action of nitric oxide synthase (NOS), is a
mediator of many diverse biological activities, including vasodilation, neurotransmission and …