Angiotensin II (AngII), the major effector peptide of renin–angiotensin system (RAS), is now
recognized as a growth factor that regulates cell growth and fibrosis, besides being a …

Transforming growth factor-β (TGF-β) participates in the pathogenesis of multiple
cardiovascular diseases, including hypertension, restenosis, atherosclerosis, cardiac …

The NF-κB family of transcription factors regulates the induction and resolution of
inflammation. Two main pathways, classical and alternative, control the nuclear …

Background The migration of monocytes into the vessel wall is a critical event leading to the
development of atherosclerosis. Monocyte chemoattractant protein-1 (MCP-1) is the main …

Background and Purpose—We sought to study overall and domain-specific quality of life in
stroke survivors 1 year after stroke and to identify variables that could predict quality of life …

Objective: Glucosamine sulfate (GS) is a commonly used drug for the treatment of
osteoarthritis. The mechanism of the action of this drug does, however, remain to be …

Objectives. To study the effect of the 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA)-
reductase inhibitor atorvastatin on the potential mechanisms involved in the recruitment of …

Background: Health-related quality of life (HRQoL) is a recognized and important outcome
after stroke. An increased survival and the presence of moderate impairment in long-term …

Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the
kidney. Background Emerging evidence suggests that angiotensin II (Ang II) is not only a …

The renin-angiotensin system (RAS) has emerged as one of the essential links in the
pathophysiology of vascular disease. Angiotensin (Ang) II, the main peptide of the RAS, was …