Update of EULAR recommendations for the treatment of systemic sclerosis

O Kowal-Bielecka, J Fransen, J Avouac… - Annals of the …, 2017 - ard.bmj.com
The aim was to update the 2009 European League against Rheumatism (EULAR)
recommendations for the treatment of systemic sclerosis (SSc), with attention to new …

Synovial fibroblasts spread rheumatoid arthritis to unaffected joints

S Lefèvre, A Knedla, C Tennie, A Kampmann… - Nature medicine, 2009 - nature.com
Active rheumatoid arthritis originates from few joints but subsequently affects the majority of
joints. Thus far, the pathways of the progression of the disease are largely unknown. As …

Measuring pain and efficacy of pain treatment in inflammatory arthritis: a systematic literature review

M Englbrecht, IH Tarner, DM van der HEIJDE… - The Journal of …, 2012 - jrheum.org
Objective. To systematically review the available literature on measuring pain and the
efficacy of pain treatment in inflammatory arthritis (IA), as an evidence base for generating …

The potential of adiponectin in driving arthritis

A Ehling, A Schäffler, H Herfarth, IH Tarner… - The Journal of …, 2006 - journals.aai.org
Articular adipose tissue is a ubiquitous component of human joints, but its local functions are
largely unknown. Because recent studies revealed several links between adipose tissue …

The different stages of synovitis: acute vs chronic, early vs late and non-erosive vs erosive

IH Tarner, P Härle, U Müller-Ladner, RE Gay… - Best practice & research …, 2005 - Elsevier
Rheumatoid arthritis is a systemic inflammatory disease that, by definition, can affect all parts
of the human body, including severe complications such as uveitis/episcleritis and vasculitis …

Drug delivery systems for the treatment of rheumatoid arthritis

IH Tarner, U Müller-Ladner - Expert opinion on drug delivery, 2008 - Taylor & Francis
Rheumatoid arthritis (RA) is a severe immune-mediated disease characterized by
chronically progressive inflammation and destruction of joints and associated structures …

Natural killer cells trigger osteoclastogenesis and bone destruction in arthritis

K Söderström, E Stein, P Colmenero… - Proceedings of the …, 2010 - National Acad Sciences
Osteoclasts are bone-eroding cells that develop from monocytic precursor cells in the
presence of receptor activator of NF-κB ligand (RANKL) and macrophage colony-stimulating …

Local production of complement proteins in rheumatoid arthritis synovium

E Neumann, SR Barnum, IH Tarner… - … : Official Journal of …, 2002 - Wiley Online Library
Objective Complement has been repeatedly implicated in the pathogenesis of rheumatoid
arthritis (RA) based on studies showing reduced levels of native complement components …

[HTML][HTML] Cell culture and passaging alters gene expression pattern and proliferation rate in rheumatoid arthritis synovial fibroblasts

E Neumann, B Riepl, A Knedla, S Lefèvre… - Arthritis research & …, 2010 - Springer
Introduction Rheumatoid arthritis synovial fibroblasts (RASF) are key players in synovial
pathophysiology and are therefore examined extensively in various experimental …

Natural killer cells trigger differentiation of monocytes into dendritic cells

AL Zhang, P Colmenero, U Purath… - Blood, The Journal …, 2007 - ashpublications.org
Circulating monocytes can differentiate into dendritic cells (moDCs), which are potent
inducers of adaptive immune responses. Previous reports show that granulocyte …