User profiles for "author:Iannis E Adamopoulos"

Iannis E. Adamopoulos

Director of Arthritis Program and Head of Osteoimmunology Laboratory
Verified email at bidmc.harvard.edu
Cited by 17176

The implication of vitamin D and autoimmunity: a comprehensive review

CY Yang, PSC Leung, IE Adamopoulos… - Clinical reviews in …, 2013 - Springer
Historically, vitamin D has been associated with the regulation of bone metabolism.
However, increasing evidence demonstrates a strong association between vitamin D …

The critical role of toll-like receptors—from microbial recognition to autoimmunity: a comprehensive review

MJ Jiménez-Dalmaroni, ME Gerswhin… - Autoimmunity …, 2016 - Elsevier
Toll-like receptors (TLRs) constitute an important mechanism in the activation of innate
immune cells including monocytes, macrophages and dendritic cells. Macrophage activation …

The IL-23/IL-17 axis in psoriatic arthritis

E Suzuki, ED Mellins, ME Gershwin, FO Nestle… - Autoimmunity …, 2014 - Elsevier
Psoriatic arthritis (PsA) is an immune-mediated chronic inflammatory disease, affecting both
the skin and joints. Disease progression is associated with aberrant cytokine expression …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

[HTML][HTML] Interleukin-17A upregulates receptor activator of NF-κB on osteoclast precursors

IE Adamopoulos, C Chao, R Geissler, D Laface… - Arthritis research & …, 2010 - Springer
Introduction The interaction between the immune and skeletal systems is evidenced by the
bone loss observed in autoimmune diseases such as rheumatoid arthritis. In this paper we …

IL-23 is critical for induction of arthritis, osteoclast formation, and maintenance of bone mass

IE Adamopoulos, M Tessmer, CC Chao… - The Journal of …, 2011 - journals.aai.org
The role of IL-23 in the development of arthritis and bone metabolism was studied using
systemic IL-23 exposure in adult mice via hydrodynamic delivery of IL-23 minicircle DNA in …

Axial spondyloarthritis: new advances in diagnosis and management

C Ritchlin, IE Adamopoulos - Bmj, 2021 - bmj.com
Axial spondyloarthritis (axSpA) is an inflammatory disease of the axial skeleton associated
with significant pain and disability. Previously, the diagnosis of ankylosing spondylitis …

Alternative pathways of osteoclastogenesis in inflammatory arthritis

IE Adamopoulos, ED Mellins - Nature Reviews Rheumatology, 2015 - nature.com
Osteoclasts are cells of haematopoietic origin that are uniquely specialized to degrade
bone. Under physiological conditions, the osteoclastogenesis pathway depends on …

Inflammation in bone physiology and pathology

IE Adamopoulos - Current opinion in rheumatology, 2018 - journals.lww.com
Inflammation in bone physiology and pathology : Current Opinion in Rheumatology
Inflammation in bone physiology and pathology : Current Opinion in Rheumatology Log in …

Autophagy and autoimmunity

DJ Wu, IE Adamopoulos - Clinical Immunology, 2017 - Elsevier
Autophagy is a highly conserved protein degradation pathway from yeasts to humans that is
essential for removing protein aggregates and misfolded proteins in healthy cells. Recently …