The pathogenesis of rheumatoid arthritis

IB McInnes, G Schett - New England Journal of Medicine, 2011 - Mass Medical Soc
The Pathogenesis of Rheumatoid Arthritis | NEJM Skip to main content NEJM Group Follow Us
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Cytokines in the pathogenesis of rheumatoid arthritis

IB McInnes, G Schett - Nature Reviews Immunology, 2007 - nature.com
Cytokines regulate a broad range of inflammatory processes that are implicated in the
pathogenesis of rheumatoid arthritis. In rheumatoid joints, it is well known that an imbalance …

COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options

TJ Guzik, SA Mohiddin, A Dimarco, V Patel… - Cardiovascular …, 2020 - academic.oup.com
The novel coronavirus disease (COVID-19) outbreak, caused by SARS-CoV-2, represents
the greatest medical challenge in decades. We provide a comprehensive review of the …

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update

JS Smolen, RBM Landewé, JWJ Bijlsma… - Annals of the …, 2020 - ard.bmj.com
Objectives To provide an update of the European League Against Rheumatism (EULAR)
rheumatoid arthritis (RA) management recommendations to account for the most recent …

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update

JS Smolen, R Landewé, J Bijlsma… - Annals of the …, 2017 - ard.bmj.com
Recent insights in rheumatoid arthritis (RA) necessitated updating the European League
Against Rheumatism (EULAR) RA management recommendations. A large international …

Treating rheumatoid arthritis to target: recommendations of an international task force

JS Smolen, D Aletaha, JWJ Bijlsma… - Annals of the …, 2010 - ard.bmj.com
Background Aiming at therapeutic targets has reduced the risk of organ failure in many
diseases such as diabetes or hypertension. Such targets have not been defined for …

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs

JS Smolen, R Landewé, FC Breedveld… - Annals of the …, 2010 - ard.bmj.com
Treatment of rheumatoid arthritis (RA) may differ among rheumatologists and currently, clear
and consensual international recommendations on RA treatment are not available. In this …

Obesity is a risk factor for severe COVID-19 infection: multiple potential mechanisms

N Sattar, IB McInnes, JJV McMurray - Circulation, 2020 - Am Heart Assoc
Circulation. 2020; 142: 4–6. DOI: 10.1161/CIRCULATIONAHA. 120.047659 July 7, 2020 5
certain ethnicities, eg, Asians. 1 Asians often display lower cardiorespiratory fitness and …

[HTML][HTML] Evidence that cytokines play a role in rheumatoid arthritis

FM Brennan, IB McInnes - The Journal of clinical …, 2008 - Am Soc Clin Investig
A large number of cytokines are active in the joints of patients with rheumatoid arthritis (RA).
It is now clear that these cytokines play a fundamental role in the processes that cause …

Explaining how “high-grade” systemic inflammation accelerates vascular risk in rheumatoid arthritis

N Sattar, DW McCarey, H Capell, IB McInnes - Circulation, 2003 - Am Heart Assoc
There is intense interest in mechanisms whereby low-grade inflammation could interact with
conventional and novel vascular risk factors to promote the atheromatous lesion. Patients …