Objectives Osteoarthritis (OA) is the most common form of arthritis with a clear genetic
component. To identify novel loci associated with hip OA we performed a meta-analysis of …

Here we describe the insights gained from sequencing the whole genomes of 2,636
Icelanders to a median depth of 20×. We found 20 million SNPs and 1.5 million insertions …

Eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation
of inflammatory responses and thus have important roles in the pathogenesis of …

The common sequence variants that have recently been associated with cancer risk are
particular to a single cancer type or at most two. Following up on our genome-wide scan of …

Ovarian cancer causes more deaths than any other gynecologic malignancy in developed
countries. Sixteen million sequence variants, identified through whole-genome sequencing …

In order to search for sequence variants conferring risk of thyroid cancer we conducted a
genome-wide association study in 192 and 37,196 Icelandic cases and controls …

Through complementary application of SNP genotyping, whole-genome sequencing and
imputation in 38,384 Icelanders, we have discovered a previously unidentified sick sinus …

Through whole-genome sequencing of 2,630 Icelanders and imputation into 11,114
Icelandic cases and 267,140 controls followed by testing in Danish and Iranian samples, we …

To identify new risk variants for cutaneous basal cell carcinoma, we performed a genome-
wide association study of 16 million SNPs identified through whole-genome sequencing of …

Low bone mineral density (BMD) is used as a parameter of osteoporosis. Genome-wide
association studies of BMD have hitherto focused on BMD as a quantitative trait, yielding …