Highly active antiretroviral therapy (HAART) increases CD4+ cell numbers, but its ability to
correct the human immunodeficiency virus (HIV)–induced immune deficiency remains …

The introduction of combined antiretroviral therapies (HAART) has reversed the fatal course
of human immunodeficiency virus (HIV) infection. HAART controls virus production and, in …

Background Current data suggest that COVID-19 is less frequent in children, with a milder
course. However, over the past weeks, an increase in the number of children presenting to …

Multicentric Castleman disease (MCD) is a distinct type of lymphoproliferative disorder
associated with inflammatory symptoms and interleukin-6 (IL-6) dysregulation. In the context …

Objectives: To test the hypothesis that an acute exacerbation of mycobacteria-specific Th1
response after HIV infection control by HAART causes immune restoration syndrome (IRS) …

Huntington disease (HD) is a fatal neurodegenerative disorder, with no effective treatment.
The pathogenic mechanisms underlying HD have not been elucidated, but weight loss …

Immune reconstitution during antiretroviral therapy has recently been shown to depend
upon multiple factors at work in T cell homeostasis, amongst which the reduction of thymus …

The mechanisms of CD4+ T-cell count decline, the hallmark of HIV disease progression, and
its relationship to elevated levels of immune activation are not fully understood. Massive …

Immune‐based therapy (IBT) interventions have found a window of opportunity within some
limitations of the otherwise successful combined antiretroviral therapy (cART). Two major …

Objective To describe the clinical and microbiological features of acute genital ulcers (AGU),
which have been reported in virgin adolescents, predominantly in girls. Design Descriptive …