Imaging biomarkers (IBs) are integral to the routine management of patients with cancer. IBs
used daily in oncology include clinical TNM stage, objective response and left ventricular …

Background Tumor spatial heterogeneity is an important prognostic factor, which may be
reflected in medical images Methods Image texture analysis is an approach of quantifying …

Radiomics is a rapidly evolving field of research concerned with the extraction of quantitative
metrics—the so-called radiomic features—within medical images. Radiomic features capture …

Background Radiomic features may quantify characteristics present in medical imaging.
However, the lack of standardized definitions and validated reference values have …

Results: 1 8 FDG PET detected more lesions than 99mTc MDP scintigraphy (mean, 14.1 and
7.8 lesions, respectively; P<. 01). However, 18 FDG detected fewer bone metastases …

Abstract 18 F-Fluorodeoxyglucose positron emission tomography/computed tomography (18
F-FDG PET/CT) is now routinely used in oncological imaging for diagnosis and staging and …

Introduction Breast cancer remains a significant scientific, clinical and societal challenge.
This gap analysis has reviewed and critically assessed enduring issues and new challenges …

There is evidence in some solid tumors that textural features of tumoral uptake in 18F-FDG
PET images are associated with response to chemoradiotherapy and survival. We have …

Aptamers are small oligonucleotides that are selected to bind tightly and specifically to a
target molecule. We sought to determine whether aptamers have potential for in vivo …

This groundbreaking study details the intellectual development of George Herbert Mead as
a thinker of great originality and as a practitioner of social reform. Gary Cook traces the …