Clinical, laboratory, radiographic, and histopathologic features of methotrexate‐associated lung injury in patients with rheumatoid arthritis. A multicenter study with …

…, M Macaluso, GW Cannon… - Arthritis & …, 1997 - Wiley Online Library
Objective. To describe the clinical, laboratory, radiologic, and histopathologic features of
methotrexate (MTX)‐induced lung injury in a combined cohort of selected patients with …

Etanercept versus methotrexate in patients with early rheumatoid arthritis: two‐year radiographic and clinical outcomes

…, AL Weaver, J Markenson, GW Cannon… - … : Official Journal of …, 2002 - Wiley Online Library
Objective To compare the clinical and radiographic outcomes in patients with rheumatoid
arthritis (RA) who received monotherapy with either etanercept or methotrexate (MTX) for 2 …

Methotrexate pulmonary toxicity

GW Cannon - Rheumatic Disease Clinics of North America, 1997 - Elsevier
The treatment of rheumatoid arthritis (RA) with methotrexate (MTX) has been a major
advance 38, 40, 52, 57, 60, 61, 62, 63, 66 Methotrexate is now the most commonly used …

Comparison of sulfasalazine and placebo in the treatment of psoriatic arthritis. A Department of Veterans Affairs Cooperative Study

DO Clegg, DJ Reda, E Mejias, GW Cannon… - Arthritis & …, 1996 - Wiley Online Library
Objective. To determine whether sulfasalazine (SSZ) at a dosage of 2,000 mg/day is
effective for the treatment of active psoriatic arthritis (PsA) resistant to nonsteroidal …

Concomitant leflunomide therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate: a randomized, double-blind, placebo-controlled trial

JM Kremer, MC Genovese, GW Cannon… - Annals of internal …, 2002 - acpjournals.org
Background: Disease-modifying antirheumatic drugs may confer greater benefits when
combined with the antimetabolite methotrexate. Objective: To evaluate the efficacy and …

[PDF][PDF] Periodontitis and Porphyromonas gingivalis in Patients With Rheumatoid Arthritis

…, GM Thiele, RJ Reynolds, GW Cannon… - Arthritis & …, 2014 - Wiley Online Library
Objective To examine the degree to which shared risk factors explain the relationship of
periodontitis (PD) to rheumatoid arthritis (RA) and to determine the associations of PD and …

Risk factors for methotrexate-induced lung injury in patients with rheumatoid arthritis: a multicenter, case-control study

…, M Macaluso, ME Weinblatt, GW Cannon… - Annals of internal …, 1997 - acpjournals.org
Background: Toxicity limits the use of methotrexate. Objective: To identify risk factors for
methotrexate-induced lung injury in patients with rheumatoid arthritis. Design: Case-control …

Two‐year, blinded, randomized, controlled trial of treatment of active rheumatoid arthritis with leflunomide compared with methotrexate

S Cohen, GW Cannon, M Schiff… - … : Official Journal of …, 2001 - Wiley Online Library
Abstract Objective Three 6–12‐month, double‐blind, randomized, controlled trials have
shown leflunomide (LEF; 20 mg/day, loading dose 100 mg× 3 days) to be effective and safe …

Comparison of sulfasalazine and placebo in the treatment of ankylosing spondylitis. A Department of Veterans Affairs Cooperative Study

…, WD Blackburn, JJ Cush, GW Cannon… - Arthritis & …, 1996 - Wiley Online Library
Objective. To determine whether sulfasalazine (SSZ) at a dosage of 2,000 mg/day is
effective for the treatment of active ankylosing spondylitis (AS) that is not controlled with …

Rheumatoid factor as a potentiator of anti–citrullinated protein antibody–mediated inflammation in rheumatoid arthritis

…, AM Reimold, L Caplan, GW Cannon… - Arthritis & …, 2014 - Wiley Online Library
Objective The co‐occurrence of rheumatoid factor (RF) and anti–citrullinated protein
antibody (ACPA) positivity in rheumatoid arthritis (RA) is well described. However, the …