The relationship between osteoarthritis and osteoporosis

GI Im, MK Kim - Journal of bone and mineral metabolism, 2014 - Springer
The relationship between osteoarthritis (OA) and osteoporosis (OP), the two most common
skeletal disorders related to aging, is controversial. Previous studies suggest that OA is …

Drug delivery systems for intra-articular treatment of osteoarthritis

ML Kang, GI Im - Expert opinion on drug delivery, 2014 - Taylor & Francis
Introduction: Intra-articular (IA) drug delivery is very useful in the treatment of osteoarthritis
(OA), the most common chronic joint affliction. However, the therapeutic effect of IA …

Mesenchymal stem cells for tissue engineering and regenerative medicine

SK Tae, SH Lee, JS Park, GI Im - Biomedical materials, 2006 - iopscience.iop.org
Mesenchymal stem cells (MSCs) exist in bone marrow and other musculoskeletal tissues.
These cells contribute to the homeostasis of musculoskeletal tissue as well as support for …

Osteoblast proliferation and maturation by bisphosphonates

GI Im, SA Qureshi, J Kenney, HE Rubash… - Biomaterials, 2004 - Elsevier
Aseptic loosening and osteolysis are currently the most common causes of failure of total
joint replacements. Osteolysis is initiated by a macrophage response to wear debris …

Distal metaphyseal fractures of tibia: a prospective randomized trial of closed reduction and intramedullary nail versus open reduction and plate and screws fixation

GI Im, SK Tae - Journal of Trauma and Acute Care Surgery, 2005 - journals.lww.com
Background: To compare closed intramedullary nailing with open plate and screw fixation
and set the indications for each treatment modality in distal metaphyseal fractures of tibia, 64 …

Repair of cartilage defect in the rabbit with cultured mesenchymal stem cells from bone marrow

GI Im, DY Kim, JH Shin, CW Hyun… - The Journal of Bone & …, 2001 - boneandjoint.org.uk
In 16 mature New Zealand white rabbits mesenchymal stem cells were aspirated from the
bone marrow, cultured in monolayer and implanted on to a full-thickness osteochondral …

Poly (norepinephrine): ultrasmooth material-independent surface chemistry and nanodepot for nitric oxide.

S Hong, J Kim, YS Na, J Park, S Kim… - Angewandte …, 2013 - search.ebscohost.com
Capture and release: The material‐independent surface chemistry of a poly
(norepinephrine)(pNE) which exhibits perfect smoothness at the nanometer scale is …

Intra-articular delivery of kartogenin-conjugated chitosan nano/microparticles for cartilage regeneration

ML Kang, JY Ko, JE Kim, GI Im - Biomaterials, 2014 - Elsevier
We developed an intra-articular (IA) drug delivery system to treat osteoarthritis (OA) that
consisted of kartogenin conjugated chitosan (CHI-KGN). Kartogenin, which promotes the …

In vitro chondrogenesis and in vivo repair of osteochondral defect with human induced pluripotent stem cells

JY Ko, KI Kim, S Park, GI Im - Biomaterials, 2014 - Elsevier
The purpose of this study was to investigate the chondrogenic features of human induced
pluripotent stem cells (hiPSCs) and examine the differences in the chondrogenesis between …

[HTML][HTML] Enhanced skin wound healing by a sustained release of growth factors contained in platelet-rich plasma

HS Yang, J Shin, SH Bhang, JY Shin, J Park… - … & molecular medicine, 2011 - nature.com
Platelet-rich plasma (PRP) contains growth factors that promote tissue regeneration.
Previously, we showed that heparin-conjugated fibrin (HCF) exerts the sustained release of …