Psoriasis is a common chronic, recurrent, immune mediated disease of the skin and joints. It
can have a significant negative impact on the physical, emotional, and, psychosocial …

There have been several articles and reports in recent months about comorbidities and risks
that affect psoriasis patients in addition to their underlying disease. This piece reviews the …

In clinical practice, broad global assessments of psoriasis disease activity and its effect on
patients' quality of life are used to assess the severity of patients' disease and their response …

Psoriasis is a common immune-mediated disorder that affects the skin, nails and joints. To
identify psoriasis susceptibility loci, we genotyped 438,670 SNPs in 1,409 psoriasis cases …

Background Ustekinumab, a human monoclonal antibody against interleukins 12 and 23,
has shown therapeutic potential for psoriasis. This study assessed the efficacy and safety of …

We performed a multitiered, case-control association study of psoriasis in three independent
sample sets of white North American individuals (1,446 cases and 1,432 controls) with …

To gain further insight into the genetic architecture of psoriasis, we conducted a meta-
analysis of 3 genome-wide association studies (GWAS) and 2 independent data sets …

Background Skin-infiltrating lymphocytes expressing type 1 cytokines have been linked to
the pathophysiology of psoriasis. We evaluated the safety and efficacy of a human …

Objectives: To evaluate further in a phase III, double blind trial the efficacy of infliximab in
patients with active psoriatic arthritis (PsA), as observed in the smaller IMPACT trial …

Objective To assess the efficacy and safety of golimumab in patients with active psoriatic
arthritis (PsA). Methods Adult patients with PsA who had at least 3 swollen and 3 tender …