User profiles for "author:Françoise Dignat-George"

DIGNAT-GEORGE Françoise

PU-PH, Aix-Marseille Université
Verified email at univ-amu.fr
Cited by 59909

Methodological guidelines to study extracellular vesicles

FAW Coumans, AR Brisson, EI Buzas… - Circulation …, 2017 - Am Heart Assoc
Owing to the relationship between extracellular vesicles (EVs) and physiological and
pathological conditions, the interest in EVs is exponentially growing. EVs hold high hopes …

The many faces of endothelial microparticles

F Dignat-George, CM Boulanger - Arteriosclerosis, thrombosis, and …, 2011 - Am Heart Assoc
Endothelial microparticles (EMP) are complex vesicular structures shed from activated or
apoptotic endothelial cells. They play a remarkable role in coagulation, inflammation …

Procoagulant microparticles: disrupting the vascular homeostasis equation?

O Morel, F Toti, B Hugel, B Bakouboula… - … , and vascular biology, 2006 - Am Heart Assoc
Apoptosis and vascular cell activation are main contributors to the release of procoagulant
microparticles (MPs), deleterious partners in atherothrombosis. Elevated levels of circulating …

[HTML][HTML] In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant

V Combes, AC Simon, GE Grau… - The Journal of …, 1999 - Am Soc Clin Investig
Microparticles (MPs) resulting from vesiculation of platelets and other blood cells have been
extensively documented in vitro and have been found in increased numbers in several …

Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events …

L Bonello, L Camoin-Jau, S Arques, C Boyer… - Journal of the American …, 2008 - jacc.org
Objectives: This study evaluates the clinical impact of adjusting the loading dose of
clopidogrel according to vasodilator-stimulated phosphoprotein (VASP) index in patients …

Extracellular vesicles in angiogenesis

D Todorova, S Simoncini, R Lacroix, F Sabatier… - Circulation …, 2017 - Am Heart Assoc
During the past decade, extracellular vesicles (EVs), which include apoptotic bodies,
microvesicles, and exosomes, have emerged as important players in cell-to-cell …

Endothelial microparticles in diseases

GN Chironi, CM Boulanger, A Simon… - Cell and tissue …, 2009 - Springer
Microparticles are submicron vesicles shed from plasma membranes in response to cell
activation, injury, and/or apoptosis. The measurement of the phospholipid content (mainly …

Circulating endothelial cells

AD Blann, A Woywodt, F Bertolini… - Thrombosis and …, 2005 - thieme-connect.com
Recent research has recognised new populations of non-hematopoïetic cells in the blood.
One of these, circulating endothelial cells (CECs), often defined by the expression of …

Direct evidence of endothelial injury in acute myocardial infarction and unstable angina by demonstration of circulating endothelial cells

M Mutin, I Canavy, A Blann, M Bory… - Blood, The Journal …, 1999 - ashpublications.org
Circulating endothelial cells (CECs) have been detected in association with endothelial
injury and therefore represent proof of serious damage to the vascular tree. Our aim was to …

Identification of CD146 as a component of the endothelial junction involved in the control of cell-cell cohesion

N Bardin, F Anfosso, JM Massé… - Blood, The Journal …, 2001 - ashpublications.org
CD146 is a cell-surface molecule belonging to the immunoglobulin superfamily and
expressed in all types of human endothelial cells. Confocal and electron microscopic …