2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis

D Van Der Heijde, S Ramiro, R Landewé… - Annals of the …, 2017 - ard.bmj.com
To update and integrate the recommendations for ankylosing spondylitis and the
recommendations for the use of tumour necrosis factor inhibitors (TNFi) in axial …

The devil in the details: the emerging role of anticitrulline autoimmunity in rheumatoid arthritis

F van Gaalen, A Ioan-Facsinay… - The Journal of …, 2005 - journals.aai.org
Rheumatoid arthritis is a chronic inflammatory autoimmune disease of unknown cause. The
immune response against citrullinated Ags has recently become the prime suspect for …

ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update

S Ramiro, E Nikiphorou, A Sepriano… - Annals of the …, 2023 - ard.bmj.com
Objectives To update the Assessment of SpondyloArthritis international Society (ASAS)-
EULAR recommendations for the management of axial spondyloarthritis (axSpA). Methods …

Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA–DRB1 shared epitope for antibodies to citrullinated proteins

TWJ Huizinga, CI Amos… - Arthritis & …, 2005 - Wiley Online Library
Objective The main genetic risk factor for rheumatoid arthritis (RA), the HLA region, has
been known for 25 years. Previous research has demonstrated, within the RA population, an …

Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis

FA Van Gaalen, J Van Aken… - … : Official Journal of …, 2004 - Wiley Online Library
Objective. The functional role of HLA class II molecules in the pathogenesis of rheumatoid
arthritis (RA) is unclear. HLA class II molecules are involved in the interaction between T and …

Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles

SP Linn-Rasker, AHM Van Der Helm-Van Mil… - Annals of the …, 2006 - ard.bmj.com
Objectives: To study the gene–environment interaction of tobacco exposure and shared
epitope on autoantibodies in patients with rheumatoid arthritis and undifferentiated arthritis …

Pathophysiology of axial spondyloarthritis: consensus and controversies

A de Koning, JW Schoones… - European journal of …, 2018 - Wiley Online Library
Background Axial spondyloarthritis (axSpA) is a common inflammatory arthritis of the
sacroiliac joints and the spine. The best‐known and most studied form of axSpA is …

Regulation of CD163 on human macrophages: cross-linking of CD163 induces signaling and activation

MM Van den Heuvel, CP Tensen… - Journal of leukocyte …, 1999 - academic.oup.com
CD163 is a member of the group B scavenger receptor cysteine-rich (SRCR) superfamily.
This study describes aspects of the tissue distribution, the regulation of expression, and …

Rheumatoid arthritis is a heterogeneous disease: evidence for differences in the activation of the STAT‐1 pathway between rheumatoid tissues

TCTM van der Pouw Kraan… - … : Official Journal of …, 2003 - Wiley Online Library
Objective To generate a molecular description of synovial tissue from rheumatoid arthritis
(RA) patients that would allow us to unravel novel aspects of pathogenesis and to identify …

Prevalence of comorbidities and evaluation of their screening in spondyloarthritis: results of the international cross-sectional ASAS-COMOSPA study

A Moltó, A Etcheto, D Van Der Heijde… - Annals of the …, 2016 - ard.bmj.com
Background Increased risk of some comorbidities has been reported in spondyloarthritis
(SpA). Recommendations for detection/management of some of these comorbidities have …