Abstract Interleukin-17 (IL-17) is a T cell cytokine spontaneously produced by cultures of
rheumatoid arthritis (RA) synovial membranes. High levels have been detected in the …

Over the last three decades, it has become clear that the role of vitamin D goes beyond the
regulation of calcium homeostasis and bone health. An important extraskeletal effect of …

The discovery that the IL-23–IL-17 immune pathway is involved in many models of
autoimmune disease has changed the concept of the role of T-helper cell subsets in the …

Topical application of imiquimod (IMQ), a TLR7/8 ligand and potent immune activator, can
induce and exacerbate psoriasis, a chronic inflammatory skin disorder. Recently, a crucial …

Abstract Objective Interleukin‐17 (IL‐17) is a proinflammatory cytokine that is expressed in
the synovium of rheumatoid arthritis (RA) patients. This T cell cytokine is implicated in the …

From a technical point of view a flow cytometer is a light detection device capable of
detecting photons of different wavelengths over a high dynamic range. In order to achieve a …

T cell IL-17 displays proinflammatory properties and is expressed in the synovium of patients
with rheumatoid arthritis. Its contribution to the arthritic process has not been identified. Here …

IL-17 is a T cell-derived proinflammatory cytokine in experimental arthritis and is a stimulator
of osteoclastogenesis in vitro. In this study, we report the effects of IL-17 overexpression …

The origin and role of IL-17, a T-cell derived cytokine, in cartilage and bone destruction
during rheumatoid arthritis (RA) remain to be clarified. In human ex vivo models, addition of …

Objective. To examine the role of endogenous interleukin‐4 (IL‐4) and interleukin‐10 (IL‐
10) and the therapeutic effect of the addition of IL‐4 and IL‐10 in early and established …