Neutrophil gelatinase‐associated lipocalin: pathophysiology and clinical applications
Neutrophil gelatinase‐associated lipocalin (NGAL), a 25 kDa protein produced by injured
nephron epithelia, is one of the most promising new markers of renal epithelial injury. In …
nephron epithelia, is one of the most promising new markers of renal epithelial injury. In …
Hypertension-induced end-organ damage: a new transgenic approach to an old problem
FC Luft, E Mervaala, DN Müller, V Gross… - …, 1999 - Am Heart Assoc
Angiotensin (Ang) II-induced organ damage has fascinated students of hypertension since
the work of Wilson and Byrom. We are investigating a double transgenic rat (dTGR) model …
the work of Wilson and Byrom. We are investigating a double transgenic rat (dTGR) model …
[HTML][HTML] Non-HLA antibodies against endothelial targets bridging allo-and autoimmunity
D Dragun, R Catar, A Philippe - Kidney international, 2016 - Elsevier
Detrimental actions of donor-specific antibodies (DSAs) directed against both major
histocompatibility antigens (human leukocyte antigen [HLA]) and specific non-HLA antigens …
histocompatibility antigens (human leukocyte antigen [HLA]) and specific non-HLA antigens …
[HTML][HTML] An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3
A Nykjaer, D Dragun, D Walther, H Vorum, C Jacobsen… - Cell, 1999 - cell.com
Steroid hormones may enter cells by diffusion through the plasma membrane. However, we
demonstrate here that some steroid hormones are taken up by receptor-mediated …
demonstrate here that some steroid hormones are taken up by receptor-mediated …
[HTML][HTML] Angiotensin II type 1–receptor activating antibodies in renal-allograft rejection
D Dragun, DN Müller, JH Bräsen… - … England Journal of …, 2005 - Mass Medical Soc
Background Antibodies against HLA antigens cause refractory allograft rejection with
vasculopathy in some, but not all, patients. Methods We studied 33 kidney-transplant …
vasculopathy in some, but not all, patients. Methods We studied 33 kidney-transplant …
T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance
U Kintscher, M Hartge, K Hess… - … , and vascular biology, 2008 - Am Heart Assoc
Background—Adipose tissue inflammation may play a critical role in the pathogenesis of
insulin resistance (IR). The present study examined the role of lymphocytes in adipose …
insulin resistance (IR). The present study examined the role of lymphocytes in adipose …
The Banff 2019 Kidney Meeting Report (I): Updates on and clarification of criteria for T cell–and antibody‐mediated rejection
The XV. Banff conference for allograft pathology was held in conjunction with the annual
meeting of the American Society for Histocompatibility and Immunogenetics in Pittsburgh …
meeting of the American Society for Histocompatibility and Immunogenetics in Pittsburgh …
[HTML][HTML] The Banff 2015 kidney meeting report: current challenges in rejection classification and prospects for adopting molecular pathology
The XIII Banff meeting, held in conjunction the Canadian Society of Transplantation in
Vancouver, Canada, reviewed the clinical impact of updates of C4d-negative antibody …
Vancouver, Canada, reviewed the clinical impact of updates of C4d-negative antibody …
Novel and conventional serum biomarkers predicting acute kidney injury in adult cardiac surgery—a prospective cohort study
Objective: To compare the value of novel with conventional serum biomarkers in the
prediction of acute kidney injury (AKI) in adult cardiac surgical patients according to …
prediction of acute kidney injury (AKI) in adult cardiac surgical patients according to …
Involvement of functional autoantibodies against vascular receptors in systemic sclerosis
G Riemekasten, A Philippe, M Näther… - Annals of the …, 2011 - ard.bmj.com
Background Systemic sclerosis (SSc) features autoimmunity, vasculopathy and tissue
fibrosis. The renin-angiotensin and endothelin systems have been implicated in …
fibrosis. The renin-angiotensin and endothelin systems have been implicated in …