Tofacitinib in juvenile idiopathic arthritis: a double-blind, placebo-controlled, withdrawal phase 3 randomised trial
Background Tofacitinib is an oral Janus kinase inhibitor. This trial assessed the efficacy and
safety of tofacitinib versus placebo in patients with polyarticular course juvenile idiopathic …
safety of tofacitinib versus placebo in patients with polyarticular course juvenile idiopathic …
Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial
Background Ixekizumab, a high-affinity interleukin-17A (IL-17A) monoclonal antibody, has
previously shown efficacy in radiographic axial spondyloarthritis (also known as ankylosing …
previously shown efficacy in radiographic axial spondyloarthritis (also known as ankylosing …
Safety and efficacy of intravenous belimumab in children with systemic lupus erythematosus: results from a randomised, placebo-controlled trial
HI Brunner, C Abud-Mendoza, DO Viola… - Annals of the …, 2020 - ard.bmj.com
Objectives This ongoing Phase-2, randomised, placebo-controlled, double-blind study
evaluated the efficacy, safety and pharmacokinetics of intravenous belimumab in childhood …
evaluated the efficacy, safety and pharmacokinetics of intravenous belimumab in childhood …
Efficacy and safety of belimumab in paediatric and adult patients with systemic lupus erythematosus: an across-study comparison
HI Brunner, C Abud-Mendoza, M Mori, CA Pilkington… - Rmd Open, 2021 - rmdopen.bmj.com
Objective To assess the efficacy and safety of belimumab in paediatric versus adult patients
with systemic lupus erythematosus (SLE). Methods We performed across-study comparisons …
with systemic lupus erythematosus (SLE). Methods We performed across-study comparisons …
Abatacept as Monotherapy and in Combination With Methotrexate in Patients With Juvenile Idiopathic Arthritis: Analysis of 2 Phase III Trials
Objective To describe the efficacy and safety data of children with polyarticular-course
juvenile idiopathic arthritis (pcJIA) treated with abatacept (ABA)+ methotrexate (MTX) or ABA …
juvenile idiopathic arthritis (pcJIA) treated with abatacept (ABA)+ methotrexate (MTX) or ABA …
FRI0181 the PLUTO study: intravenous belimumab in children with systemic lupus erythematosus
N Ruperto, C Abud-Mendoza, DO Viola, I Calvo… - 2019 - ard.bmj.com
Background: Belimumab (BEL), a monoclonal antibody targeting the B-lymphocyte
stimulator, is approved in adults with active systemic lupus erythematosus (SLE). This is the …
stimulator, is approved in adults with active systemic lupus erythematosus (SLE). This is the …