The worldwide incidence and prevalence of psoriasis is poorly understood. To better
understand this, we performed a systematic review of published population-based studies …

Rheumatoid arthritis (RA) is the most common chronic inflammatory joint disease. There is
some evidence that it may have been brought from North America to Europe during the 18th …

The excess risk of cardiovascular disease (CVD) associated with inflammatory rheumatic
diseases has long been recognized. Patients with established rheumatoid arthritis (RA) or …

Objectives. To evaluate the risk of serious infections (SIs) in patients with RA treated with
anti-TNF therapy with emphasis on the risk across different ages. Methods. Using data from …

The major histocompatibility complex (MHC) on chromosome 6 is associated with
susceptibility to more common diseases than any other region of the human genome …

Background. Anti-tumour necrosis factor-α (TNF-α) therapies represent an important
advancement in therapy for rheumatoid arthritis (RA). However, there remains a proportion …

Objective To determine the degree and causes of any excess mortality observed during the
early years of inflammatory polyarthritis (IP). Methods Between 1990 and 1994, a total of …

Objective. To examine a range of demographic, social, and clinical risk factors for the
development of rheumatoid arthritis (RA). Results. The controls were of higher …

Low back pain in adolescents is perceived to be uncommon in the clinic setting. However,
previous studies have suggested that it may be an important and increasing problem in this …

Objective Patients with rheumatoid arthritis (RA) who experience treatment failure with one
anti–tumor necrosis factor (anti‐TNF) agent, due to either inefficacy or toxicity, are frequently …