The fetal origins hypothesis states that fetal undernutrition in middle to late gestation, which
leads to disproportionate fetal growth, programmes later coronary heart disease. Animal …

In this contribution we put forward a novel hypothesis concerning the aetiology of Type 2
(non-insulin-dependent) diabetes mellitus. The concept underlying our hypothesis is that …

Babies who are small at birth or during infancy have increased rates of cardiovascular
disease and non-insulin-dependent diabetes as adults. Some of these babies have low …

Previous studies have demonstrated that allelic deletions of the short arm of chromosome 17
occur in over 75% of colorectal carcinomas. Twenty chromosome 17p markers were used to …

In national samples of 9921 10 year olds and 3259 adults in Britain systolic blood pressure
was inversely related to birth weight. The association was independent of gestational age …

Environmental influences that impair growth and development in early life may be risk
factors for ischaemic heart disease. To test this hypothesis, 5654 men born during 1911-30 …

Although the rise in ischaemic heart disease in England and Wales has been associated
with increasing prosperity, mortality rates are highest in the least affluent areas. On division …

OBJECTIVE--To discover whether reduced fetal and infant growth is associated with non-
insulin dependent diabetes and impaired glucose tolerance in adult life. DESIGN--Follow up …

Abstract On August 17, 2017 at 12∶ 41: 04 UTC the Advanced LIGO and Advanced Virgo
gravitational-wave detectors made their first observation of a binary neutron star inspiral …

The thrifty phenotype hypothesis proposes that the epidemiological associations between
poor fetal and infant growth and the subsequent development of type 2 diabetes and the …