Sudden sensorineural hearing loss
BE Schreiber, C Agrup, DO Haskard, LM Luxon - The Lancet, 2010 - thelancet.com
Sudden sensorineural hearing loss is usually unilateral and can be associated with tinnitus
and vertigo. In most cases the cause is not identified, although various infective, vascular …
and vertigo. In most cases the cause is not identified, although various infective, vascular …
Mechanisms of inflammation in gout
N Dalbeth, DO Haskard - Rheumatology, 2005 - academic.oup.com
The clinical manifestations of gout are due to interactions between monosodium urate
(MSU) crystals and local tissues. This review article outlines recent advances in the …
(MSU) crystals and local tissues. This review article outlines recent advances in the …
Differential diagnosis and management of Behçet syndrome
NL Ambrose, DO Haskard - Nature Reviews Rheumatology, 2013 - nature.com
Behçet syndrome (also known as Behçet disease) is a rare condition that is associated with
considerable morbidity. Cases of Behçet syndrome have been reported worldwide, but the …
considerable morbidity. Cases of Behçet syndrome have been reported worldwide, but the …
Association of maternal endothelial dysfunction with preeclampsia
ContextPreeclampsia is believed to result from release of placental factors that damage
maternal vascular endothelium. However, because most studies have been conducted …
maternal vascular endothelium. However, because most studies have been conducted …
Endothelial von Willebrand factor regulates angiogenesis
RD Starke, F Ferraro, KE Paschalaki… - Blood, The Journal …, 2011 - ashpublications.org
The regulation of blood vessel formation is of fundamental importance to many physiological
processes, and angiogenesis is a major area for novel therapeutic approaches to diseases …
processes, and angiogenesis is a major area for novel therapeutic approaches to diseases …
Proinflammatory activation of macrophages by basic calcium phosphate crystals via protein kinase C and MAP kinase pathways: a vicious cycle of inflammation and …
Basic calcium phosphate (BCP) crystal deposition underlies the development of arterial
calcification. Inflammatory macrophages colocalize with BCP deposits in developing …
calcification. Inflammatory macrophages colocalize with BCP deposits in developing …
Expression of intercellular adhesion molecule-1 in atherosclerotic plaques.
RN Poston, DO Haskard, JR Coucher… - The American journal …, 1992 - ncbi.nlm.nih.gov
Immunohistochemistry of human atherosclerotic arteries demonstrates expression of the
intercellular adhesion molecule-1 (ICAM-1) on endothelial cells, macrophages, and smooth …
intercellular adhesion molecule-1 (ICAM-1) on endothelial cells, macrophages, and smooth …
Hemoglobin scavenger receptor CD163 mediates interleukin-10 release and heme oxygenase-1 synthesis: antiinflammatory monocyte-macrophage responses in …
P Philippidis, JC Mason, BJ Evans, I Nadra… - Circulation …, 2004 - Am Heart Assoc
The recently described hemoglobin scavenger receptor CD163 mediates the endocytosis of
hemoglobin: haptoglobin (Hb: Hp) complexes and thereby counters Hb-induced oxidative …
hemoglobin: haptoglobin (Hb: Hp) complexes and thereby counters Hb-induced oxidative …
Coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype
JJ Boyle, HA Harrington, E Piper, K Elderfield… - The American journal of …, 2009 - Elsevier
Intraplaque hemorrhage accelerates atherosclerosis via oxidant stress and contributes to
lesion development and destabilization. Normally, macrophages scavenge hemoglobin …
lesion development and destabilization. Normally, macrophages scavenge hemoglobin …
Elevation of plasma high-density lipoprotein concentration reduces interleukin-1–induced expression of E-selectin in an in vivo model of acute inflammation
GW Cockerill, TY Huehns, A Weerasinghe, C Stocker… - Circulation, 2001 - Am Heart Assoc
Background—Although there is strong evidence that plasma HDL levels correlate inversely
with the incidence of coronary artery disease, the precise mechanism (s) for the protective …
with the incidence of coronary artery disease, the precise mechanism (s) for the protective …