It is now clear that vitamin D has important roles in addition to its classic effects on calcium
and bone homeostasis. As the vitamin D receptor is expressed on immune cells (B cells, T …

Objectives Treat-to-target recommendations have identified 'remission'as a target in
systemic lupus erythematosus (SLE), but recognise that there is no universally accepted …

Multiple systemic lupus erythematosus cohorts have low vitamin D levels. The physiologic
and clinical consequences of vitamin D deficiency in systemic lupus erythematosus are not …

Abstract Objective The Systemic Lupus International Collaborating Clinics (SLICC) group
revised and validated the American College of Rheumatology (ACR) systemic lupus …

Background Since anecdotal series and small, prospective, controlled trials suggest that
mycophenolate mofetil may be effective for treating lupus nephritis, larger trials are …

Background and aims We studied damage accrual and factors determining development
and progression of damage in an international cohort of systemic lupus erythematosus …

Objective. To determine nephritis outcomes in a prospective multi-ethnic/racial SLE
inception cohort. Methods. Patients in the Systemic Lupus International Collaborating Clinics …

Objective To assess the effects of the B lymphocyte stimulator (BLyS)–specific inhibitor
belimumab on immunologic biomarkers, including B cell and T cell populations, and …

Objective Analysis of peripheral B cell subsets in patients with systemic lupus erythematosus
(SLE) has provided evidence of specific alterations, such as an expansion of CD27++ …

The inappropriate expansion and activation of autoreactive memory B cells and
plasmablasts contributes to loss of self-tolerance in systemic lupus erythematosus (SLE) …