Corticosteroid-induced osteoporosis is the most common form of secondary osteoporosis
and the first cause in young people. Bone loss and increased rate of fractures occur early …

The European League Against Rheumatism (EULAR) and the European Federation of
National Associations of Orthopaedics and Traumatology (EFORT) have recognised the …

Osteoporosis is classified as a public health problem by healthcare authorities because it is
associated with an increased risk of potentially serious fractures. Osteoporotic fractures are …

Background Osteoporotic structural damage and bone fragility result from reduced bone
formation and increased bone resorption. In a phase 2 clinical trial, strontium ranelate, an …

Background Risedronate increases bone mineral density in elderly women, but whether it
prevents hip fracture is not known. Methods We studied 5445 women 70 to 79 years old who …

Background Long-term safety and efficacy of osteoporosis treatment are important because
of the chronic nature of the disease. We aimed to assess the long-term safety and efficacy of …

The detection of microaneurysms in digital color fundus photographs is a critical first step in
automated screening for diabetic retinopathy (DR), a common complication of diabetes. To …

OBJECTIVE: To investigate the prevalence and incidence of clinical fractures in obese,
postmenopausal women enrolled in the Global Longitudinal study of Osteoporosis in …

Denosumab reduces bone resorption and vertebral and nonvertebral fracture risk.
Denosumab discontinuation increases bone turnover markers 3 months after a scheduled …

Patients treated with bisphosphonates for osteoporosis may discontinue or require a switch
to other therapies. Denosumab binds to RANKL and is a potent inhibitor of bone resorption …