[HTML][HTML] Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome …

E Wheeler, A Leong, CT Liu, MF Hivert… - PLoS …, 2017 - journals.plos.org
Background Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and
assess glycemic control in patients with diabetes. Previous genome-wide association …

Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index

W Wen, W Zheng, Y Okada, F Takeuchi… - Human molecular …, 2014 - academic.oup.com
Recent genetic association studies have identified 55 genetic loci associated with obesity or
body mass index (BMI). The vast majority, 51 loci, however, were identified in European …

[HTML][HTML] The 5p15. 33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia

CA Hsiung, Q Lan, YC Hong, CJ Chen… - PLoS …, 2010 - journals.plos.org
Genome-wide association studies of lung cancer reported in populations of European
background have identified three regions on chromosomes 5p15. 33, 6p21. 33, and 15q25 …

[HTML][HTML] A pilot randomized controlled trial to improve geriatric frailty

DCD Chan, HH Tsou, RS Yang, JY Tsauo, CY Chen… - BMC geriatrics, 2012 - Springer
Background Few randomized controlled trials (RCTs) report interventions targeting
improvement of frailty status as an outcome. Methods This RCT enrolled 117 older adults …

[PDF][PDF] A polymorphism in the β1 adrenergic receptor is associated with resting heart rate

K Ranade, E Jorgenson, WHH Sheu, D Pei… - The American Journal of …, 2002 - cell.com
Resting heart rate is significantly associated with cardiovascular morbidity and mortality.
However, the extent to which resting heart rate is genetically determined is poorly …

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride …

CN Spracklen, P Chen, YJ Kim, X Wang… - Human molecular …, 2017 - academic.oup.com
Large-scale meta-analyses of genome-wide association studies (GWAS) have identified>
175 loci associated with fasting cholesterol levels, including total cholesterol (TC), high …

[HTML][HTML] Prevalence and correlates of geriatric frailty in a northern Taiwan community

CI Chang, DC Chan, KN Kuo, CA Hsiung… - Journal of the Formosan …, 2011 - Elsevier
Background/Purpose Frailty is the core of geriatric syndromes in the elderly. However, there
is no solid prevalence data in Taiwan even with the rapid growth of the elderly population …

High serum iron is associated with increased cancer risk

CP Wen, JH Lee, YP Tai, C Wen, SB Wu, MK Tsai… - Cancer research, 2014 - AACR
Epidemiologic studies linking high serum iron with cancer risks are limited and inconclusive,
despite evidence implicating body iron in human carcinogenesis. A cohort of 309,443 adults …

G enetic variants associated with longer telomere length are associated with increased lung cancer risk among never‐smoking women in Asia: a report from the …

MJ Machiela, CA Hsiung, XO Shu… - … journal of cancer, 2015 - Wiley Online Library
Recent evidence from several relatively small nested case‐control studies in prospective
cohorts shows an association between longer telomere length measured phenotypically in …

Integrated care for geriatric frailty and sarcopenia: a randomized control trial

DC Chan, HH Tsou, CB Chang… - Journal of cachexia …, 2017 - Wiley Online Library
Background Exercise, nutrition, and psychological interventions may all have positive
impacts on frailty and sarcopenia. However, it is not known whether an integrated care …