Background Aiming at therapeutic targets has reduced the risk of organ failure in many
diseases such as diabetes or hypertension. Such targets have not been defined for …

We aimed to develop evidence-based multinational recommendations for the diagnosis and
management of gout. Using a formal voting process, a panel of 78 international …

Objectives To summarise existing evidence on a target oriented approach for rheumatoid
arthritis (RA) treatment. Methods We conducted a systematic literature search including all …

Different viral agents are associated with an increased risk of more severe disease course
and respiratory complications in immunocompromised patients. 1–3 The recent outbreak of …

Objectives. This study aimed to evaluate the usefulness of a systematic musculoskeletal
ultrasonographic (US) assessment in the detection of residual disease activity in patients …

Background Although targeted biological treatments have transformed the outlook for
patients with rheumatoid arthritis, 40% of patients show poor clinical response, which is …

Background: Steroids are the standard treatment for polymyalgia rheumatica. The efficacy of
the candidate drug methotrexate has not yet been demonstrated in controlled studies …

CXCL13 and CCL21 have been functionally implicated in lymphoid tissue organization both
in the upstream phases of lymphoid tissue embryogenesis and in ectopic lymphoid …

Objective: To evaluate the safety and effectiveness of adalimumab alone or in combination
with standard disease-modifying antirheumatic drugs (DMARDs) for the treatment of …

Objective: This study aimed to assess the role of Tocilizumab therapy (TCZ) in terms of ICU
admission and mortality rate of critically ill patients with severe COVID-19 pneumonia …