Acute gout attacks produce severe joint pain and inflammation associated with monosodium
urate (MSU) crystals leading to oxidative stress production. The transient potential receptor …

Objective Gout is a common cause of inflammatory arthritis and is provoked by the
accumulation of monosodium urate (MSU) crystals. However, the underlying mechanisms of …

Ultraviolet B (UVB) irradiation mainly affects biological tissues by inducing an increase in
reactive oxygen species (ROS) production which leads to deleterious outcomes for the skin …

The transient receptor potential ankyrin 1 (TRPA1) has been identified as a relevant target
for the development of novel analgesics. Gallic acid (GA) is a polyphenolic compound …

Ethnopharmacological relevance Viola tricolor, popularly known as heartsease has been
empirically used in several skin disorders, including burns. Aim of the study The objective of …

Objective. The aim of the present study was to investigate the participation of TRPV1 in an
acute gout attack model. Methods. Experiments were conducted to evaluate the participation …

Objective Verify the role of the kinin B1 receptors (B1R) and the effect of ACE inhibitors
(ACEi) on acute gout induced by monosodium urate (MSU) crystals in rodents. Methods …

Objective The present study aimed to elucidate the mechanisms involved in MSU-induced IL-
1β release in a rodent animal model of acute gout arthritis. Methods Painful (mechanical and …

Vitamin E (vit-E) is a lipophilic antioxidant, and its anti-inflammatory activity is still not full
characterized. Thus, our goal was to investigate the anti-inflammatory effect of repeated vit-E …

Background: Interest in pecan (Carya illinoensis) nut shells, a by-product of the nut industry,
has increased due to its anti-inflammatory and antioxidant activities. The goal of this study …