Angiogenesis is de novo capillary outgrowth from pre-existing blood vessels. This process
not only is crucial for normal development, but also has an important role in supplying …

Angiogenesis is essential during development and in pathological conditions such as
chronic inflammation and cancer progression. Inhibition of angiogenesis by targeting …

Angiogenesis plays a crucial role in the pathogenesis of inflammatory diseases, including
rheumatoid arthritis (RA). Therefore, targeting neovascularization in RA may hold great …

Objective. Angiogenesis is crucial in RA disease progression. Lymphotoxin β receptor
(LTβR)-induced activation of the non-canonical nuclear factor-κB (NF-κB) pathway via NF-κB …

Tertiary lymphoid structures (TLSs) in chronic inflammation, including rheumatoid arthritis
(RA) synovial tissue (ST), often contain high endothelial venules and follicular dendritic cells …

Genome-wide association studies linked expression of the human neutrophil antigen 3b
(HNA-3b) epitope on the Slc44a2 protein with a 30% decreased risk of venous thrombosis …

Background Genome wide association studies (GWAS) identified SLC44A2 as a novel
susceptibility gene for venous thrombosis (VT) and previous work established that SLC44A2 …

Background and aims Neovascularization is associated with atherosclerotic plaque
instability and increased chance of myocardial infarction (MI). Patients with chronic …

ABSTRACT NF-κB-inducing kinase (NIK; also known as MAP3K14) is a central regulator of
non-canonical NF-κB signaling in response to stimulation of TNF receptor superfamily …

Introduction Recent genome wide association studies (GWAS) identified a novel
susceptibility locus for thrombosis, harbouring the SLC44A2 gene which encodes the Solute …