User profiles for "author:C. Stehouwer"

C Stehouwer

Hoogleraar interne geneeskunde, universiteit maastricht
Verified email at mumc.nl
Cited by 130701

Vascular complications in diabetes mellitus: the role of endothelial dysfunction

CG Schalkwijk, CDA Stehouwer - Clinical science, 2005 - portlandpress.com
The endothelium is a complex organ with a multitude of properties essential for control of
vascular functions. Dysfunction of the vascular endothelium is regarded as an important …

Depression and the risk for cardiovascular diseases: systematic review and meta analysis

…, H Marwijk, H Marten, C Stehouwer… - … Journal of Geriatric …, 2007 - Wiley Online Library
Background Depression and cardiovascular diseases are both common among elderly.
Depression is suspected to be an independent risk factor for the onset of coronary heart …

[HTML][HTML] Arterial stiffness in diabetes and the metabolic syndrome: a pathway to cardiovascular disease

CDA Stehouwer, RMA Henry, I Ferreira - Diabetologia, 2008 - Springer
Increased arterial stiffness associated with diabetes and the metabolic syndrome may in part
explain the increased cardiovascular disease risk observed in these conditions. Arterial …

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

U Võsa, A Claringbould, HJ Westra, MJ Bonder… - Nature …, 2021 - nature.com
Trait-associated genetic variants affect complex phenotypes primarily via regulatory
mechanisms on the transcriptome. To investigate the genetics of gene expression, we …

C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose …

JS Yudkin, CDA Stehouwer, JJ Emeis… - … , and vascular biology, 1999 - Am Heart Assoc
C-reactive protein, a hepatic acute phase protein largely regulated by circulating levels of
interleukin-6, predicts coronary heart disease incidence in healthy subjects. We have shown …

Common carotid intima-media thickness measurements in cardiovascular risk prediction: a meta-analysis

HM Den Ruijter, SAE Peters, TJ Anderson, AR Britton… - Jama, 2012 - jamanetwork.com
Context The evidence that measurement of the common carotid intima-media thickness
(CIMT) improves the risk scores in prediction of the absolute risk of cardiovascular events is …

Association of cardiometabolic multimorbidity with mortality

E Di Angelantonio, S Kaptoge, D Wormser, P Willeit… - Jama, 2015 - jamanetwork.com
Importance The prevalence of cardiometabolic multimorbidity is increasing. Objective To
estimate reductions in life expectancy associated with cardiometabolic multimorbidity …

Metabolic syndrome and 10-year cardiovascular disease risk in the Hoorn Study

JM Dekker, C Girman, T Rhodes, G Nijpels… - Circulation, 2005 - Am Heart Assoc
Background—Different definitions of the metabolic syndrome have been proposed. Their
value in a clinical setting to assess cardiovascular disease (CVD) risk is still unclear. We …

Associations of C-reactive protein with measures of obesity, insulin resistance, and subclinical atherosclerosis in healthy, middle-aged women

AE Hak, CDA Stehouwer, ML Bots… - … , and vascular biology, 1999 - Am Heart Assoc
Obesity, the insulin resistance syndrome, and atherosclerosis are closely linked and may all
be determinants of an increased acute-phase response. In this study, we examined the …

Hyperglycaemia is associated with all-cause and cardiovascular mortality in the Hoorn population: the Hoorn Study

F De Vegt, JM Dekker, HG Ruhe, CDA Stehouwer… - Diabetologia, 1999 - Springer
Aims/hypothesis. The degree of glycaemia has been shown to be associated with all-cause
and cardiovascular mortality in diabetic subjects. Whether this association also exists in the …