Predicting the development of clinical arthritis in anti-CCP positive individuals with non-specific musculoskeletal symptoms: a prospective observational cohort study
C Rakieh, JL Nam, L Hunt, EMA Hensor… - Annals of the …, 2015 - ard.bmj.com
Objectives To monitor progression to inflammatory arthritis (IA) in individuals with non-
specific musculoskeletal (MSK) symptoms and positive anticyclic citrullinated peptide (anti …
specific musculoskeletal (MSK) symptoms and positive anticyclic citrullinated peptide (anti …
Brief report: shortened telomere length in patients with systemic lupus erythematosus
S Haque, C Rakieh, F Marriage, P Ho… - Arthritis & …, 2013 - Wiley Online Library
Objective Patients with systemic lupus erythematosus (SLE) have a higher rate of premature
death compared to the general population, suggesting a phenotype of premature …
death compared to the general population, suggesting a phenotype of premature …
Diagnosis and treatment of gout in primary care
C Rakieh, PG Conaghan - The Practitioner, 2011 - go.gale.com
GOUT IS THE HOST COHHON FORH OF INFLAMMATORY ARTHRITIS IN HEN OVER 40,
and affects up to 1-2% of adults in developed countries.(1) It is characterised by recurrent …
and affects up to 1-2% of adults in developed countries.(1) It is characterised by recurrent …
Tofacitinib for treatment of rheumatoid arthritis
C Rakieh, PG Conaghan - Advances in therapy, 2013 - Springer
The management of rheumatoid arthritis has seen a dramatic improvement with the
introduction of a range of biological disease modifying anti-rheumatic drugs (DMARDs) in …
introduction of a range of biological disease modifying anti-rheumatic drugs (DMARDs) in …
Progression of subclinical and clinical cardiovascular disease in a UK SLE cohort: the role of classic and SLE-related factors
S Haque, S Skeoch, C Rakieh, H Edlin… - Lupus Science & …, 2018 - lupus.bmj.com
Objectives We aimed to describe the rate and determinants of carotid plaque progression
and the onset of clinical cardiovascular disease (CVD) in a UK SLE cohort. Methods Female …
and the onset of clinical cardiovascular disease (CVD) in a UK SLE cohort. Methods Female …
Effect of Fatigue, Older Age, Higher Body Mass Index, and Female Sex on Disability in Early Rheumatoid Arthritis in the Treatment‐to‐Target Era
…, R Thomas, LA Bissell, C Rakieh… - Arthritis care & …, 2018 - Wiley Online Library
Objective To compare disease activity and disability over 2 years in early rheumatoid
arthritis (RA) before and after implementation of treat‐to‐target therapy and identify …
arthritis (RA) before and after implementation of treat‐to‐target therapy and identify …
Comparative clinical utility of once-weekly subcutaneous abatacept in the management of rheumatoid arthritis
C Rakieh, PG Conaghan - Therapeutics and Clinical Risk …, 2014 - Taylor & Francis
Biologic therapies in rheumatoid arthritis are now part of standard practice for disease that
proves difficult to control with conventional disease-modifying anti-rheumatic drugs. While …
proves difficult to control with conventional disease-modifying anti-rheumatic drugs. While …
Abatacept reduces disease activity and ultrasound power Doppler in ACPA-negative undifferentiated arthritis: a proof-of-concept clinical and imaging study
MH Buch, EMA Hensor, C Rakieh, JE Freeston… - …, 2016 - academic.oup.com
Objectives. No proven treatment exists for ACPA-negative undifferentiated arthritis (UA). The
aim of this study was to evaluate whether abatacept is effective in treating poor prognosis …
aim of this study was to evaluate whether abatacept is effective in treating poor prognosis …
THU0136 Long term outcomes of stopping tumour necrosis factor inhibitors (TNFI) in patients with established rheumatoid arthritis (RA) who are in sustained …
C Rakieh, B Saleem, K Takase, JL Nam… - Annals of the …, 2013 - ard.bmj.com
Background Previous research has shown that cessation of TNFi in patients with established
RA who are in sustained remission is associated with an increased risk of flare. However, it …
RA who are in sustained remission is associated with an increased risk of flare. However, it …
[HTML][HTML] Emergence of proinflammatory autoreactive T-cell responses in preclinical rheumatoid arthritis
Background 5 million people suffer from rheumatoid arthritis (RA) and every year 25 000
people will develop this disease in the UK. In an emerging model, the pathogenesis of RA …
people will develop this disease in the UK. In an emerging model, the pathogenesis of RA …