Objective To perform a mechanistic study on the effect of interleukin (IL)-1 blockade by
anakinra in patients with refractory myositis and to explore possible predictive biomarkers …

OBJECTIVE: To evaluate the diagnostic yield, performance simplicity, and safety of the
percutaneous conchotome muscle biopsy technique for clinical and research purposes in an …

The inflammatory myopathies–myositis–encompass a heterogeneous group of chronic
muscle disorders of unknown origin and with varying prognoses. New clinical phenotypes of …

Abstract Objective Interleukin‐1 (IL‐1) acts via its receptors to induce gene expression that
mediates protein synthesis involved in inflammation. Increased expression of IL‐1α and IL …

Objectives: To determine whether muscle weakness is correlated with inflammation,
expression of interleukin 1α (IL1α) and major histocompatibility complex (MHC) class I and II …

Objectives: To investigate the expression of microsomal prostaglandin E (PGE) synthase 1
(mPGES-1) and cyclooxygenase (COX) in muscle biopsies from patients with polymyositis or …

Background In chronic inflammatory diseases, IL-1 is known as an important
proinflammatory cytokine inducing the expression of a variety of genes mediating the …

Objectives: To investigate the expression of microsomal PGE synthase 1 (mPGES-1) and
cyclooxygenase (COX) in muscle biopsies from patients with polymyositis or …

The purpose of this thesis is to highlight the phenomenon of “Sex for Grades” in Liberian
universities as an intrinsically relevant category of study by illuminating the relationships …

The idiopathic inflammatory myopathies (IIM): polymyositis (PM), dermatomyositis (DM) and
inclusion body myositis (IBM) are chronic rheumatic muscle diseases of unknown origin that …