2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus

M Aringer, K Costenbader, D Daikh… - Arthritis & …, 2019 - Wiley Online Library
Objective To develop new classification criteria for systemic lupus erythematosus (SLE)
jointly supported by the European League Against Rheumatism (EULAR) and the American …

Long-lived autoreactive plasma cells drive persistent autoimmune inflammation

F Hiepe, T Dörner, AE Hauser, BF Hoyer… - Nature Reviews …, 2011 - nature.com
Aberrant production of autoantibodies by inappropriately self-reactive plasma cells is an
inherent characteristic of autoimmune diseases. Several therapeutic strategies aim to …

SARS–CoV‐2 infection and COVID‐19 outcomes in rheumatic diseases: a systematic literature review and meta‐analysis

R Conway, AA Grimshaw, MF Konig… - Arthritis & …, 2022 - Wiley Online Library
Objective The relative risk of SARS–CoV‐2 infection and COVID‐19 disease severity among
people with rheumatic and musculoskeletal diseases (RMDs) compared to those without …

Guidelines for the use of flow cytometry and cell sorting in immunological studies*

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2017 - Wiley Online Library
From a technical point of view a flow cytometer is a light detection device capable of
detecting photons of different wavelengths over a high dynamic range. In order to achieve a …

Immunogenicity and safety of anti-SARS-CoV-2 mRNA vaccines in patients with chronic inflammatory conditions and immunosuppressive therapy in a monocentric …

UM Geisen, DK Berner, F Tran, M Sümbül… - Annals of the …, 2021 - ard.bmj.com
Introduction In light of the SARS-CoV-2 pandemic, protecting vulnerable groups has become
a high priority. Persons at risk of severe disease, for example, those receiving …

Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice

BF Hoyer, K Moser, AE Hauser, A Peddinghaus… - Arthritis Res Ther, 2004 - Springer
Background La/SSB is a phosphoprotein that associates with various small RNA molecules.
It has been found that the primary phosphorylation site of the molecule during various …

Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response

M Odendahl, H Mei, BF Hoyer, AM Jacobi, A Hansen… - Blood, 2005 - ashpublications.org
Maintenance of protective humoral immunity depends on the generation and survival of
antibody-secreting cells. The bone marrow provides niches for long-term survival of plasma …

The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosus

T Alexander, R Sarfert, J Klotsche, AA Kühl… - Annals of the …, 2015 - ard.bmj.com
Objectives To investigate whether bortezomib, a proteasome inhibitor approved for
treatment of multiple myeloma, induces clinically relevant plasma cell (PC) depletion in …

Early experience of COVID-19 vaccination in adults with systemic rheumatic diseases: results from the COVID-19 Global Rheumatology Alliance Vaccine Survey

SE Sattui, JW Liew, K Kennedy, E Sirotich… - RMD open, 2021 - rmdopen.bmj.com
Background We describe the early experiences of adults with systemic rheumatic disease
who received the COVID-19 vaccine. Methods From 2 April to 30 April 2021, we conducted …

Memory B and memory plasma cells

T Yoshida, H Mei, T Dörner, F Hiepe… - Immunological …, 2010 - Wiley Online Library
Vaccination provides a powerful means to control infections. It exploits and exemplifies the
ability of the immune system to preserve the information that a specific pathogen has been …