The role of miRNA in inflammation and autoimmunity

RP Singh, I Massachi, S Manickavel, S Singh… - Autoimmunity …, 2013 - Elsevier
Abstract miRNAs are small non-coding RNA molecules that modulate the expression of
multiple protein-encoding genes at the post-transcriptional level. They have recently been …

The pathogenesis of atherosclerosis in autoimmune rheumatic diseases: roles of inflammation and dyslipidemia

BH Hahn, J Grossman, W Chen, M McMahon - Journal of autoimmunity, 2007 - Elsevier
As patients with autoimmune rheumatic diseases live longer due to improved therapies and
preventive measures, death and disability from atherosclerosis, particularly myocardial …

Th17 cells in inflammation and autoimmunity

RP Singh, S Hasan, S Sharma, S Nagra… - Autoimmunity …, 2014 - Elsevier
Abstract T helper 17 (Th17), a distinct subset of CD4+ T cells with IL-17 as their major
cytokine, orchestrate the pathogenesis of inflammatory and autoimmune diseases …

[HTML][HTML] Combined oral contraceptives in women with systemic lupus erythematosus

M Petri, MY Kim, KC Kalunian… - … England Journal of …, 2005 - Mass Medical Soc
Background Oral contraceptives are rarely prescribed for women with systemic lupus
erythematosus, because of concern about potential negative side effects. In this double …

American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis

BH Hahn, MA Mcmahon, A Wilkinson… - Arthritis care & …, 2012 - Wiley Online Library
In the US, approximately 35% of adults with systemic lupus erythematosus (SLE) have
clinical evidence of nephritis at the time of diagnosis, with an estimated total of 50–60 …

The effect of combined estrogen and progesterone hormone replacement therapy on disease activity in systemic lupus erythematosus: a randomized trial

JP Buyon, MA Petri, MY Kim, KC Kalunian… - Annals of internal …, 2005 - acpjournals.org
Background: There is concern that exogenous female hormones may worsen disease
activity in women with systemic lupus erythematosus (SLE). Objective: To evaluate the effect …

Association of increased interferon‐inducible gene expression with disease activity and lupus nephritis in patients with systemic lupus erythematosus

X Feng, H Wu, JM Grossman… - Arthritis & …, 2006 - Wiley Online Library
Objective To study 5 type I interferon (IFN)–inducible genes (LY6E, OAS1, OASL, MX1, and
ISG15) in patients with systemic lupus erythematosus (SLE) and to correlate expression …

Proinflammatory high‐density lipoprotein as a biomarker for atherosclerosis in patients with systemic lupus erythematosus and rheumatoid arthritis

M McMahon, J Grossman, J FitzGerald… - … : Official Journal of …, 2006 - Wiley Online Library
Objective Women with systemic lupus erythematosus (SLE) have a 7–50‐fold increased risk
of coronary artery disease (CAD). In the general population, oxidized low‐density lipoprotein …

Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus

N Shen, Q Fu, Y Deng, X Qian, J Zhao… - Proceedings of the …, 2010 - National Acad Sciences
Systemic lupus erythematosus (SLE) is a multisystem, autoimmune disease that
predominantly affects women. Previous findings that duplicated Toll-like receptor 7 (Tlr7) …

A multicenter study of outcome in systemic lupus erythematosus. ii.

S Rosner, EM Ginzler, HS Diamond… - … : Official Journal of …, 1982 - Wiley Online Library
Causes of death were examined for 1,103 systemic lupus erythematosus patients who were
followed from 1965 to 1978 at 9 centers that participated in the Lupus Survival Study Group …