User profiles for "author:B Kidd"

Brian A. Kidd

Scientific Senior Director, Predictive Sciences at Bristol-Myers Squibb
Verified email at bms.com
Cited by 8715

Mechanisms of inflammatory pain

BL Kidd, LA Urban - British journal of anaesthesia, 2001 - bjanaesthesia.org
One of the cardinal features of inflammatory states is that normally innocuous stimuli
produce pain. Since the publication of the Melzack±Wall gate control theory in 1965, 45 it …

In silico methods for drug repurposing and pharmacology

RA Hodos, BA Kidd, K Shameer… - … Systems Biology and …, 2016 - Wiley Online Library
Data in the biological, chemical, and clinical domains are accumulating at ever‐increasing
rates and have the potential to accelerate and inform drug development in new ways …

Parahydrogen‐based hyperpolarization for biomedicine

JB Hövener, AN Pravdivtsev, B Kidd… - Angewandte Chemie …, 2018 - Wiley Online Library
Magnetic resonance (MR) is one of the most versatile and useful physical effects used for
human imaging, chemical analysis, and the elucidation of molecular structures. However, its …

[HTML][HTML] Deep patient: an unsupervised representation to predict the future of patients from the electronic health records

R Miotto, L Li, BA Kidd, JT Dudley - Scientific reports, 2016 - nature.com
Secondary use of electronic health records (EHRs) promises to advance clinical research
and better inform clinical decision making. Challenges in summarizing and representing …

A new social movement: Sport for development and peace

B Kidd - Sport in society, 2008 - Taylor & Francis
In recent years, national and international sports organizations, governments and non-
governmental organizations (NGOs), universities and schools have conducted programmes …

Towards a mechanism-based classification of pain?

CJ Woolf, GJ Bennett, M Doherty, R Dubner, B Kidd… - Pain, 1998 - journals.lww.com
It is self evident that the recent explosive growth in our understanding of the molecular,
cellular and system's mechanisms responsible for nociception and pain has important …

A rat model of bone cancer pain

SJ Medhurst, K Walker, M Bowes, BL Kidd, M Glatt… - Pain, 2002 - journals.lww.com
This study describes the first known model of bone cancer pain in the rat. Sprague–Dawley
rats receiving intra-tibial injections of syngeneic MRMT-1 rat mammary gland carcinoma …

Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite

M Platten, PP Ho, S Youssef, P Fontoura, H Garren… - Science, 2005 - science.org
Local catabolism of the amino acid tryptophan (Trp) by indoleamine 2, 3-dioxygenase (IDO)
is considered an important mechanism of regulating T cell immunity. We show that IDO …

[PDF][PDF] Virus-specific CD4+ memory-phenotype T cells are abundant in unexposed adults

LF Su, BA Kidd, A Han, JJ Kotzin, MM Davis - Immunity, 2013 - cell.com
Although T cell memory is generally thought to require direct antigen exposure, we found an
abundance of memory-phenotype cells (20%–90%, averaging over 50%) of CD4+ T cells …

Pain related behaviour in two models of osteoarthritis in the rat knee

…, M Malcangio, A Fox, J Rediske, T Pellas, B Kidd… - Pain, 2004 - Elsevier
Osteoarthritis (OA) is a major healthcare burden, with increasing incidence. Pain is the
predominant clinical feature, yet therapy is ineffective for many patients. While there are …