Osteoporosis and mortality

A Leboime, CB Confavreux, N Mehsen, J Paccou… - Joint bone spine, 2010 - Elsevier
Osteoporosis is classified as a public health problem by healthcare authorities because it is
associated with an increased risk of potentially serious fractures. Osteoporotic fractures are …

Faecal microbiota study reveals specific dysbiosis in spondyloarthritis

M Breban, J Tap, A Leboime, R Said-Nahal… - Annals of the …, 2017 - ard.bmj.com
Objective Altered microbiota composition or dysbiosis is suspected to be implicated in the
pathogenesis of chronic inflammatory diseases, such as spondyloarthritis (SpA) and …

Both disease activity and HLA–B27 status are associated with gut microbiome dysbiosis in spondyloarthritis patients

M Berland, V Meslier, S Berreira Ibraim… - Arthritis & …, 2023 - Wiley Online Library
Objective Gut microbiome dysbiosis has previously been reported in spondyloarthritis (SpA)
patients and could be critically involved in the pathogenesis of this disorder. The objectives …

COVID-19 in French patients with chronic inflammatory rheumatic diseases: clinical features, risk factors and treatment adherence

F Costantino, L Bahier, LC Tarancón, A Leboime… - Joint Bone Spine, 2021 - Elsevier
Objective To explore how patients with chronic inflammatory rheumatic diseases (CIRDs)
coped with their disease during the COVID-19 pandemic and to identify possible predictive …

Severity of osteoporosis: what is the impact of co-morbidities?

C David, CB Confavreux, N Mehsen, J Paccou… - Joint Bone Spine, 2010 - Elsevier
The co-morbidity profile varies widely across postmenopausal women with osteoporosis,
and comorbidities often adversely affect the management of osteoporosis. There is a need …

ERAP1 Gene Expression Is Influenced by Nonsynonymous Polymorphisms Associated With Predisposition to Spondyloarthritis

F Costantino, A Talpin, I Evnouchidou… - Arthritis & …, 2015 - Wiley Online Library
Objective Several polymorphisms in ERAP1 are strongly associated with susceptibility to
spondyloarthritis (SpA). The combination of rs17482078, rs10050860, and rs30187 results …

Investigating the genetic association between ERAP1 and spondyloarthritis

A Kadi, B Izac, R Said-Nahal, A Leboime… - Annals of the …, 2013 - ard.bmj.com
Objective A robust association between polymorphisms in the non-major histocompatibility
complex gene ERAP1 and ankylosing spondylitis (AS) in several populations was recently …

[HTML][HTML] Monocyte-derived dendritic cells from HLA-B27+ axial spondyloarthritis (SpA) patients display altered functional capacity and deregulated gene expression

A Talpin, F Costantino, N Bonilla, A Leboime… - Arthritis research & …, 2014 - Springer
Introduction This study aimed to compare the functional capacity and gene expression
profile of monocyte-derived dendritic cells (MD-DCs) in HLA-B27+ axial spondyloarthritis …

Correspondence between patient-reported flare and disease activity score variation in axial spondyloarthritis: a 12-months web-based study

F Costantino, A Leboime, L Bessalah, M Breban - Joint Bone Spine, 2022 - Elsevier
Objective The aims of this study were to determine thresholds of variations of BASDAI and
pain associated with patient-reported outbreak or resolution of flare and to test performance …

Brief Report: The IL23R Nonsynonymous Polymorphism rs11209026 Is Associated With Radiographic Sacroiliitis in Spondyloarthritis

A Kadi, F Costantino, B Izac, A Leboime… - Arthritis & …, 2013 - Wiley Online Library
Objective Spondyloarthritis (SpA) is a group of inflammatory articular disorders sharing a
genetic background. The nonsynonymous single‐nucleotide polymorphism (SNP) …