EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid …
The Study Group for Risk Factors for Rheumatoid Arthritis was established by the EULAR
Standing Committee on Investigative Rheumatology to facilitate research into the preclinical …
Standing Committee on Investigative Rheumatology to facilitate research into the preclinical …
[HTML][HTML] Advances in the genetics of rheumatoid arthritis point to subclassification into distinct disease subsets
AHM van der Helm-van Mil, TWJ Huizinga - Arthritis research & therapy, 2008 - Springer
In the past few years considerable advances have been made in the genetics of
susceptibility to rheumatoid arthritis (RA). For decades the HLA-DRB1 alleles were the only …
susceptibility to rheumatoid arthritis (RA). For decades the HLA-DRB1 alleles were the only …
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
EA Stahl, S Raychaudhuri, EF Remmers, G Xie… - Nature …, 2010 - nature.com
To identify new genetic risk factors for rheumatoid arthritis, we conducted a genome-wide
association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid …
association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid …
Preventing progression from arthralgia to arthritis: targeting the right patients
HW Van Steenbergen, JAP Da Silva… - Nature Reviews …, 2018 - nature.com
Early treatment is associated with improved outcomes in patients with rheumatoid arthritis
(RA), suggesting that a'window of opportunity', in which the disease is most susceptible to …
(RA), suggesting that a'window of opportunity', in which the disease is most susceptible to …
Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage
Autoimmune responses against posttranslationally modified antigens are a hallmark of
several autoimmune diseases. For example, antibodies against citrullinated protein antigens …
several autoimmune diseases. For example, antibodies against citrullinated protein antigens …
Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA–DRB1 shared epitope for antibodies to citrullinated proteins
TWJ Huizinga, CI Amos… - Arthritis & …, 2005 - Wiley Online Library
Objective The main genetic risk factor for rheumatoid arthritis (RA), the HLA region, has
been known for 25 years. Previous research has demonstrated, within the RA population, an …
been known for 25 years. Previous research has demonstrated, within the RA population, an …
Common variants at CD40 and other loci confer risk of rheumatoid arthritis
S Raychaudhuri, EF Remmers, AT Lee, R Hackett… - Nature …, 2008 - nature.com
To identify rheumatoid arthritis risk loci in European populations, we conducted a meta-
analysis of two published genome-wide association (GWA) studies totaling 3,393 cases and …
analysis of two published genome-wide association (GWA) studies totaling 3,393 cases and …
Long‐term impact of delay in assessment of patients with early arthritis
MPM Van Der Linden, S Le Cessie… - Arthritis & …, 2010 - Wiley Online Library
Objective During the last decade, rheumatologists have learned to initiate disease‐
modifying antirheumatic drugs (DMARDs) early to improve the outcome of rheumatoid …
modifying antirheumatic drugs (DMARDs) early to improve the outcome of rheumatoid …
[HTML][HTML] Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis
AHM van der Helm-van Mil, KN Verpoort… - Arthritis research & …, 2005 - Springer
Antibodies to citrullinated proteins (anti-cyclic-citrullinated peptide [anti-CCP] antibodies) are
highly specific for rheumatoid arthritis (RA) and precede the onset of disease symptoms …
highly specific for rheumatoid arthritis (RA) and precede the onset of disease symptoms …
2016 update of the EULAR recommendations for the management of early arthritis
Objectives Since the 2007 recommendations for the management of early arthritis have
been presented, considerable research has been published in the field of early arthritis …
been presented, considerable research has been published in the field of early arthritis …