In the 18th century, Thomas Bayes developed his eponymous theorem that teaches us that
pretest probabilities can be altered by new information, such as when game show host …

The successfully functioning brain is a heavy user of metabolic energy. Alzheimer's disease,
in which cognitive faculties decline, may be due, at least in part, to metabolic insufficiency …

Objective To optimise a strategy for identifying gene expression signatures differentiating
systemic lupus erythematosus (SLE) and antineutrophil cytoplasmic antibody-associated …

Background For expression profiling to have a practical impact in the management of
immune-related disease it is essential that it can be applied to peripheral blood cells. Early …

Autoimmune diseases are common and debilitating, but their severe manifestations could
be reduced if biomarkers were available to allow individual tailoring of the potentially toxic …

Severe injury in mammals initiates a complex neurohormonal and metabolic response
which results in profound alterations in fuel substrate utilization. A major feature of this …