Synovial macrophages are one of the resident cell types in synovial tissue and while they
remain relatively quiescent in the healthy joint, they become activated in the inflamed joint …

Objective To assess blood vessel stability in inflammatory synovial tissue (ST) and to
examine neural cell adhesion molecule (NCAM), oxidative DNA damage, and hypoxia in …

Objective To investigate the relationship between acute‐phase serum amyloid A (A‐SAA)
and joint destruction in inflammatory arthritis. Methods Serum A‐SAA and C‐reactive protein …

Objectives To assess levels of oxidative DNA damage (8-oxo-7, 8-dihydro-2′-
deoxyguanine; 8-oxo-dG) and lipid peroxidation (4-hydroxy-2-nonenal; 4-HNE) in serum …

Objective To examine the effect of hypoxia on Notch‐1 signaling pathway components and
angiogenesis in inflammatory arthritis. Methods The expression and regulation of Notch‐1 …

Introduction To examine the effects of tumour necrosis factor (TNF) blocking therapy on the
levels of early mitochondrial genome alterations and oxidative stress. Methods Eighteen …

Objective To examine the effect of tumor necrosis factor (TNF) blocking therapy on hypoxia
in vivo, macroscopic and microscopic inflammation, and magnetic resonance imaging (MRI) …

In response to the EU Third Directive on Non-Life Insurance, the Irish Government has
introduced legislation which effectively opens the voluntary private health insurance market …

Mortality Trends in Ireland Page 1 Mortality Trends in Ireland 13th June 2007 Demographic
Sub-Committee: John Armstrong (Chairperson) Colm Guiry Aisling Kennedy Liam Sloyan …

Background Hypoxia and oxidative stress are involved in mediating angiogenic processes
in the inflamed synovial tissue. In this study we examine the expression of angiogenic …