User profiles for "author:AW Morgan"

Ann W Morgan

- Verified email at leeds.ac.uk - Cited by 28316

Abby R. Whittington

- Verified email at vt.edu - Cited by 3148

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

…, X Ke, AT Lee, X Liu, P Martin, AW Morgan… - Nature …, 2010 - nature.com
To identify new genetic risk factors for rheumatoid arthritis, we conducted a genome-wide
association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid …

The mechanical properties and osteoconductivity of hydroxyapatite bone scaffolds with multi-scale porosity

JR Woodard, AJ Hilldore, SK Lan, CJ Park, AW Morgan… - Biomaterials, 2007 - Elsevier
The relative osteoconductivity and the change in the mechanical properties of
hydroxyapatite (HA) scaffolds with multi-scale porosity were compared to scaffolds with a …

Should I send my patient with previous giant cell arteritis for imaging of the thoracic aorta? A systematic literature review and meta-analysis

SL Mackie, EMA Hensor, AW Morgan… - Annals of the rheumatic …, 2014 - ard.bmj.com
Objectives To review the literature in order to estimate how many previously unknown
thoracic aortic aneurysms (TAAs) and thoracic aortic dilatations (TADs) might be detected by …

The effect of endogenous cushing syndrome on all-cause and cause-specific mortality

P Limumpornpetch, AW Morgan… - The Journal of …, 2022 - academic.oup.com
Objective We aimed to perform a systematic review and meta-analysis of all-cause and
cause-specific mortality of patients with benign endogenous Cushing syndrome (CS) …

The requirement for DNAM-1, NKG2D, and NKp46 in the natural killer cell-mediated killing of myeloma cells

…, TD Holmes, D McGonagle, SL Mackie, AW Morgan… - Cancer research, 2007 - AACR
Recent evidence suggests a role for natural killer (NK) cells in the control of multiple
myeloma. We show that expression of the NK cell receptor DNAM-1 (CD226) is reduced on …

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

…, AT Lee, X Liu, Y Li, P Martin, AW Morgan… - Nature …, 2009 - nature.com
To discover new rheumatoid arthritis (RA) risk loci, we systematically examined 370 SNPs
from 179 independent loci with P< 0.001 in a published meta-analysis of RA genome-wide …

Association of rheumatoid factor and anti-cyclic citrullinated peptide positivity, but not carriage of shared epitope or PTPN22 susceptibility variants, with anti-tumour …

…, J Worthington, P Emery, AW Morgan… - Annals of the …, 2009 - ard.bmj.com
Objective: To determine whether rheumatoid factor (RF), anti-cyclic citrullinated peptide
(CCP) antibodies, or carriage of shared epitope (SE) and PTPN22 genetic susceptibility …

Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients

…, R Weinshilboum, A Barton, AW Morgan… - The …, 2018 - nature.com
Methotrexate (MTX) monotherapy is a common first treatment for rheumatoid arthritis (RA),
but many patients do not respond adequately. In order to identify genetic predictors of …

Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake

…, EC Jolly, R Watts, YL Lau, AW Morgan… - The Journal of …, 2008 - rupress.org
Copy number (CN) variation (CNV) has been shown to be common in regions of the
genome coding for immune-related genes, and thus impacts upon polygenic autoimmunity …

[HTML][HTML] Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis

…, IN Bruce, J Bluett, M Feletar, AW Morgan… - Nature …, 2015 - nature.com
Psoriatic arthritis (PsA) is a chronic inflammatory arthritis associated with psoriasis and,
despite the larger estimated heritability for PsA, the majority of genetic susceptibility loci …