Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
…, X Ke, AT Lee, X Liu, P Martin, AW Morgan… - Nature …, 2010 - nature.com
To identify new genetic risk factors for rheumatoid arthritis, we conducted a genome-wide
association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid …
association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid …
The mechanical properties and osteoconductivity of hydroxyapatite bone scaffolds with multi-scale porosity
JR Woodard, AJ Hilldore, SK Lan, CJ Park, AW Morgan… - Biomaterials, 2007 - Elsevier
The relative osteoconductivity and the change in the mechanical properties of
hydroxyapatite (HA) scaffolds with multi-scale porosity were compared to scaffolds with a …
hydroxyapatite (HA) scaffolds with multi-scale porosity were compared to scaffolds with a …
Should I send my patient with previous giant cell arteritis for imaging of the thoracic aorta? A systematic literature review and meta-analysis
SL Mackie, EMA Hensor, AW Morgan… - Annals of the rheumatic …, 2014 - ard.bmj.com
Objectives To review the literature in order to estimate how many previously unknown
thoracic aortic aneurysms (TAAs) and thoracic aortic dilatations (TADs) might be detected by …
thoracic aortic aneurysms (TAAs) and thoracic aortic dilatations (TADs) might be detected by …
The effect of endogenous cushing syndrome on all-cause and cause-specific mortality
P Limumpornpetch, AW Morgan… - The Journal of …, 2022 - academic.oup.com
Objective We aimed to perform a systematic review and meta-analysis of all-cause and
cause-specific mortality of patients with benign endogenous Cushing syndrome (CS) …
cause-specific mortality of patients with benign endogenous Cushing syndrome (CS) …
The requirement for DNAM-1, NKG2D, and NKp46 in the natural killer cell-mediated killing of myeloma cells
…, TD Holmes, D McGonagle, SL Mackie, AW Morgan… - Cancer research, 2007 - AACR
Recent evidence suggests a role for natural killer (NK) cells in the control of multiple
myeloma. We show that expression of the NK cell receptor DNAM-1 (CD226) is reduced on …
myeloma. We show that expression of the NK cell receptor DNAM-1 (CD226) is reduced on …
Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk
To discover new rheumatoid arthritis (RA) risk loci, we systematically examined 370 SNPs
from 179 independent loci with P< 0.001 in a published meta-analysis of RA genome-wide …
from 179 independent loci with P< 0.001 in a published meta-analysis of RA genome-wide …
Association of rheumatoid factor and anti-cyclic citrullinated peptide positivity, but not carriage of shared epitope or PTPN22 susceptibility variants, with anti-tumour …
Objective: To determine whether rheumatoid factor (RF), anti-cyclic citrullinated peptide
(CCP) antibodies, or carriage of shared epitope (SE) and PTPN22 genetic susceptibility …
(CCP) antibodies, or carriage of shared epitope (SE) and PTPN22 genetic susceptibility …
Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients
…, R Weinshilboum, A Barton, AW Morgan… - The …, 2018 - nature.com
Methotrexate (MTX) monotherapy is a common first treatment for rheumatoid arthritis (RA),
but many patients do not respond adequately. In order to identify genetic predictors of …
but many patients do not respond adequately. In order to identify genetic predictors of …
Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake
Copy number (CN) variation (CNV) has been shown to be common in regions of the
genome coding for immune-related genes, and thus impacts upon polygenic autoimmunity …
genome coding for immune-related genes, and thus impacts upon polygenic autoimmunity …
[HTML][HTML] Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis
Psoriatic arthritis (PsA) is a chronic inflammatory arthritis associated with psoriasis and,
despite the larger estimated heritability for PsA, the majority of genetic susceptibility loci …
despite the larger estimated heritability for PsA, the majority of genetic susceptibility loci …