This study attempted to simulate the drinking habits of gout patients. Beer or squash was
drunk over a 4-hour period on two successive days by five gouty and five normouricaemic …

To determine whether patients with gout have a diet which is distinctive in quality or quantity
a careful dietary questionnaire was posed over 7 days to 61 men with gout and 52 control …

1. The pharmacokinetic and pharmacodynamic properties of oral glibenclamide have been
studied in 31 hospitalised in‐patients and 79 ambulant out‐patients with diabetes mellitus …

An enzyme capable of degrading 5'-methylthioadenosine to adenine was found in the
human erythrocyte. A rapid assay for this enzyme, 5'-methylthioadenosine phosphorylase …

The dose of allopurinol necessary to induce sustained normouricaemia in gout rarely
exceeds 300 mg daily. We describe a patient with apparent resistance to conventional …

In a metabolic ward study of five patients, azapropazone lowered plasma uric acid but
exerted only a modest and variable uricosuric effect without altering urinary xanthine and …

Patients with chronic gouty arthritis unresponsive to allopurinol are generally dismissed as
poor compliers. This paper presents studies in a middle-aged male with a 20-year history of …

A relationship between hyperuricaemia, gout and excessive alcohol consumption is well
established. The increase of serum lactate which follows alcohol ingestion may impair renal …

A novel method for measuring AMP‐deaminase activity in human erythrocytes is presented,
based on the determination of the reaction product, IMP, using high performance liquid …

Papers 1 Amiloride disposition in geriatric patients: importance of renal function: A. Somogyi,
D. Hewson, M. Muirhead & F. Bochner 9 Tianeptine binding to human plasma proteins and …