[HTML][HTML] The human hookworm vaccine

PJ Hotez, D Diemert, KM Bacon, C Beaumier… - Vaccine, 2013 - Elsevier
Hookworm infection is one of the world's most common neglected tropical diseases and a
leading cause of iron deficiency anemia in low-and middle-income countries. A Human …

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

Australo-Anglo-American Spondyloarthritis … - Nature …, 2011 - nature.com
Ankylosing spondylitis is a common form of inflammatory arthritis predominantly affecting the
spine and pelvis that occurs in approximately 5 out of 1,000 adults of European descent …

Measurement uncertainty and conformity assessment applied to drug and medicine analyses–a review

L Separovic, RS Simabukuro, AR Couto… - Critical Reviews in …, 2023 - Taylor & Francis
Analytical results are often used in scientific research, industrial and clinical applications to
support decision making. Despite all efforts to ensure the reliability of analytical results …

[HTML][HTML] Contribution of KIR3DL1/3DS1 to ankylosing spondylitis in human leukocyte antigen-B27 Caucasian populations

C Lopez-Larrea, MA Blanco-Gelaz… - Arthritis research & …, 2006 - Springer
Killer cell immunoglobulin-like receptors (KIRs) and humaAn leukocyte antigen (HLA) loci
are both highly polymorphic, and some HLA class I molecules bind and trigger cell-surface …

Ectopic calcification among families in the Azores: clinical and radiologic manifestations in families with diffuse idiopathic skeletal hyperostosis and chondrocalcinosis

J Bruges‐Armas, AR Couto, A Timms… - Arthritis & …, 2006 - Wiley Online Library
Objective Twelve families that were multiply affected with diffuse idiopathic skeletal
hyperostosis (DISH) and/or chondrocalcinosis, were identified on the island of Terceira, The …

The role of HLA-DRB1 alleles on susceptibility and outcome of a Portuguese Multiple Sclerosis population

AM Silva, C Pereira, A Bettencourt, C Carvalho… - Journal of the …, 2007 - Elsevier
BACKGROUND: The association between susceptibility to multiple sclerosis (MS) and HLA-
DRB1⁎ 15 has been reported in various European populations. OBJECTIVE: To investigate …

A Novel LEMD3 Mutation Common to Patients with Osteopoikilosis With and Without Melorheostosis

AR Couto, J Bruges-Armas, CA Peach… - Calcified tissue …, 2007 - Springer
Recent studies have reported loss of function mutations in the LEMD3 gene, encoding an
inner nuclear membrane protein that influences Smad signaling, as a cause of …

[HTML][HTML] Evidence for a genetic contribution to the ossification of spinal ligaments in Ossification of Posterior Longitudinal Ligament and Diffuse idiopathic skeletal …

AR Couto, B Parreira, DM Power, L Pinheiro… - Frontiers in …, 2022 - frontiersin.org
Diffuse Idiopathic Skeletal Hyperostosis (DISH) and Ossification of the Posterior
Longitudinal Ligament (OPLL) are common disorders characterized by the ossification of …

HLA-E, HLA-F and HLA-G—the non-classical side of the MHC cluster

I Foroni, AR Couto, BF Bettencourt… - HLA and Associated …, 2014 - books.google.com
Traditionally, the MHC is divided into the classes containing groups of genes with related
functions; the MHC class I and II genes encode for human leukocyte antigens (HLA) …

Non-classical human leucocyte antigens in ankylosing spondylitis: possible association with HLA-E and HLA-F

MR Santos, AR Couto, I Foroni, BF Bettencourt, Z Li… - RMD open, 2018 - rmdopen.bmj.com
Objectives Ankylosing spondylitis (AS) is the most prevalent form of spondyloarthritis, with a
known genetic association with the HLA-B27 molecule. The aim of this study was to assess …